Role of specialized nutrition for wound healing: a narrative review

Role of specialized nutrition for wound healing: a narrative review

Authors

  • Angelo Cianciulli Sapienza University of Rome 00185, Italy
  • Alessandro Delli Poggi Department of Biomedicine and Prevention, Tor Vergata University of Rome, 00173 Italy; Department of Surgical Sciences University of Rome 00185, Italy
  • Noemi Giannetta Department of Biomedicine and Prevention, Tor Vergata University of Rome, 00173 Italy
  • Massimo Fiorinelli Sapienza University of Rome 00185, Italy
  • Emanuela Taraborelli Sapienza University of Rome 00185, Italy
  • Antonella Roncone Sapienza University of Rome 00185, Italy
  • Raissa Biasiucci Sapienza University of Rome 00185, Italy
  • Mariachiara Figura Sapienza University of Rome 00185, Italy
  • Emanuele Di Simone Department of Biomedicine and Prevention, Tor Vergata University of Rome, 00173 Italy
  • Marco Di Muzio Department of Clinical and Molecular Medicine, Sapienza University of Rome 00185, Italy

Keywords:

Leucine; Sarcopenia; HMB; Supplements; Specialized Nutrition.

Abstract

Background. Wound healing is a dynamic process that depends not only on the interaction between different cellular factors involved in the tissue repair process but can also be adjuvant by a daily nutritional support. Therefore it can be considered a kind of specialized nutrition of which several elements favour the repair and wound healing process. Objective: The aim of this study was to verify the effect of beta-hydroxy-beta-methylbutyrate (HMB). To investigate the effects of the combination of arginine, beta-hydroxy-beta-methylbutyrate and glutamine in order to favour collagen deposition on the wound bed. Materials and Methods: The research was conducted by analysing publications of recent years and also by setting “title and abstract” as a search criterion. Results: From the studies conducted, it was shown that by analysing the combined action of the amino acid mixture in relation to collagen deposition in humans, in just two weeks the integration with arginine, HMB and glutamine produced a significant increase in plasma levels of arginine and ornithine equal to 67%. Conclusions: HMB increases lean mass, improves muscle strength and exerts anti-catabolism. Glutamine is essential in the metabolism of lymphocytes, enterocytes and other cells with a rapid turnover. Collagen synthesis and scar formation are necessary for complete resolution of a wound.

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Published

18-09-2019

Issue

Section

Reviews

How to Cite

1.
Cianciulli A, Delli Poggi A, Giannetta N, Fiorinelli M, Taraborelli E, Roncone A, et al. Role of specialized nutrition for wound healing: a narrative review. Progr Nutr [Internet]. 2019 Sep. 18 [cited 2025 Feb. 19];21(3):507-12. Available from: https://mattioli1885journals.com/index.php/progressinnutrition/article/view/7280

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