The effect of Nigella sativa on infertility in men and women: a systematic review

The effect of Nigella sativa on infertility in men and women: a systematic review

Authors

  • Mina Darand Student Research Commitee, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Behehshti University of Medical Sciences, Tehran, Iran
  • Parvin Mirmiran Department Of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran 19395-4741, Iran.
  • Amin Mokari-Yamchi Department Of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Amin Mokari-Yamchi Department Of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Keywords:

Nigella Sativa, Black Seed, Thymoquinone, Infertility, Reproductive System, Reproductive Parameters

Abstract

Bobjective: Black seed (Nigella sativa L.) is a medicinal plant belonging to botanical family of Ranunculaceae. Given the effective role of N. sativa in treating different diseases, the present systematic review aimed to evaluate the effects of N. sativa on the reproductive system. Materials and Methods: The current systematic review was carried out on randomized controlled trials (RCTs) regarding human, animal and in vivo/in vitro studies published between 2014 and 2017. The related articles were collected by searching the databases of Medline, PubMed, Scopus, Science direct, and Google scholar only in English using the search keywords of Nigella sativa, Black Seed, Thymoquinone (TQ), Infertility, Reproductive System and Reproductive Parameters. Review articles, case reports, abstract in symposium and congress were excluded. Results: Finally, 24 articles were selected for analyses. The results showed that the treatment with N. sativa has improved the sperm parameters, semen fluid in men and leydig cell count, graph follicle count, corpus luteum and level of sex hormones such as testosterone and progesterone in women (p<0.05). Conclusion: According to the findings, N. sativa can improve the reproductive parameters and sex hormones in both genders.

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Published

23-01-2020

Issue

Vol. 21 No. 2-S (2019): Supplement 2/2019: Community nutrition from childhood to old age

Section

Reviews

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

1.
Darand M, Mirmiran P, Mokari-Yamchi A, Mokari-Yamchi A. The effect of Nigella sativa on infertility in men and women: a systematic review. Progr Nutr [Internet]. 2020 Jan. 23 [cited 2025 Mar. 3];21(2-S):33-41. Available from: https://mattioli1885journals.com/index.php/progressinnutrition/article/view/7088
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