Dietary creatine-guanidinoacetate acutely improves circulating creatine levels and running performance in healthy men and women: Creatine-guanidinoacetate for creatine status and exercise performance

Bogdan Andjelic; Nikola Todorovic; Milan Vranes; Sergej Ostojic

doi:10.23751/pn.v26i1.14886

Dietary creatine-guanidinoacetate acutely improves circulating creatine levels and running performance in healthy men and women

Creatine-guanidinoacetate for creatine status and exercise performance

Authors

Bogdan Andjelic University of Novi Sad
Nikola Todorovic University of Novi Sad
Milan Vranes University of Novi Sad
Sergej Ostojic University of Novi Sad

DOI: https://doi.org/10.23751/pn.v26i1.14886

Keywords:

Creatine, Guanidinoacetate, Exercise, Bioenergetics, Women

Abstract

N/A

References

Ostojic SM, Forbes SC. Perspective: creatine, a conditionally essential nutrient: building the case. Adv Nutr. 2022;13(1):34-37.

Stajer V, Trivic T, Drid P, Vranes M, Ostojic SM. A single session of exhaustive exercise markedly decreases circulating levels of guanidinoacetic acid in healthy men and women. Appl Physiol Nutr Metab 2016;41(10):1100-1103.

Stajer V, Vranes M, Ostojic SM. Correlation between biomarkers of creatine metabolism and serum indicators of peripheral muscle fatigue during exhaustive exercise in active men. Res Sports Med. 2020;28(1):147-154.

Joncquel-Chevalier Curt M, Cheillan D, Briand G, et al. Creatine and guanidinoacetate reference values in a French population. Mol Genet Metab. 2013;110(3):263-7.

Jovanov P, Vranes M, Sakac M, et al. Hydrophilic interaction chromatography coupled to tandem mass spectrometry as a method for simultaneous determination of guanidinoacetate and creatine. Analytica Chimica Acta. 2018;1028:96-103.

Semeredi S, Stajer V, Ostojic J, Vranes M, Ostojic SM. Guanidinoacetic acid with creatine compared with creatine alone for tissue creatine content, hyperhomocysteinemia, and exercise performance: a randomized, double-blind superiority trial. Nutrition. 2019;57:162-166.

Ostojic SM. Co-administration of creatine and guanidinoacetic acid for augmented tissue bioenergetics: a novel approach? Biomed Pharmacother. 2017;91:238-240.

Ostojic SM, Jorga J. Guanidinoacetic acid in human nutrition: beyond creatine synthesis. Food Sci Nutr. 2023 Jan 11;11(4):1606-1611.

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Published

26-03-2024

Issue

Vol. 26 No. 1 (2024)

Section

Letters to Editor

License

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How to Cite

Andjelic B, Todorovic N, Vranes M, Ostojic S. Dietary creatine-guanidinoacetate acutely improves circulating creatine levels and running performance in healthy men and women: Creatine-guanidinoacetate for creatine status and exercise performance . Progr Nutr [Internet]. 2024 Mar. 26 [cited 2025 Feb. 22];26(1):e2024003. Available from: https://mattioli1885journals.com/index.php/progressinnutrition/article/view/14886