Medicinal and Nutritional Analysis of Fig (Ficus carica) Seed Oil; A New Gamma Tocopherol and Omega-3 Source

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Nefise Baygeldi
Rana Nagihan Akder
Özlem Çağındı


Ficus Carica, Fig Seed Oil, Omega-3, Gamma Tocopherol


Ficus carica (common fig) is a tree native to southwest Asia and the eastern Mediterranean and is among the first plants cultivated by humans. Fig harvest is of worldwide importance for their dry and fresh consumption. The fruit, roots, and leaves of figs are used as anti-inflammatory and antispasmodic drugs for treating various disorders such as gastrointestinal (colic, dyspepsia, anorexia, and diarrhea), respiratory (a sore throat, cough, and bronchial problems) and cardiovascular disorders in traditional medicine. Previous studies have reported the use of latex, leaves, fruit, and root of the fig in the literature. However, so far, fig seeds (Ficus carica) have not been decomposed and analyzed for their oil content. High-Performance Chromatography Fluorescence Detector (HPLC-FLD) method was used to measure the level of vitamin E tocopherol, and the fatty acid content was analyzed with Gas Chromatography with Flame Ionization Detector (GC-FID) method. The results showed that Ficus carica seed oil is a rich source of linolenic acid (C18:3), linoleic acid (C18:2) and oleic acid (C18:1). Besides, it contains 314.61±51.53 mg/100 g gamma tocopherol. Thus, Ficus carica seed oil is of importance in the health sciences.


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1. Duke JA, Bugenschutz-Godwin MJ, duCellier J, Duke PK. Hand Book of Medicinal Herbs, 2nd Ed., Boca Raton, Florida, USA: CRC Press LLC, 2002.
2. Tous J, Ferguson L. Mediterranean fruits. In: Janick, J (ed.). Progress in new crops, ASHS Press, Arlington; 1996. pp. 416-430.
3. Penelope, O. 100 Great Natural Remedies Using Healing, New York, NY, USA: Kyle Cathic Limited; 1997.
4. Guarrera PM. Traditional phytotherapy in Central Italy (Marche, Abruzzo, and Latium). Fitoterapia 2005;76(1):1–25.
5. Lansky EP, Paavilainen HM, Pawlus AD, Newman RA. Ficus spp. (fig): Ethnobotany and potential as anticancer and anti-inflammatory agents. Journal of Ethnopharmacology 2008;119(2):195-213.
6. Joseph B, Raj SJ. Pharmacognostic and phytochemical properties of Ficus carica Linn–An overview. International Journal of Pharm Tech Research 2011;3(1):08-12.
7. Badgujar SB, Patel VV, Bandivdekar AH, Mahajan RT. Traditional uses, phytochemistry and pharmacology of Ficus carica: A review. Pharm Biol 2014;52(11):1487-1503.
8. Rahmani AH, Aldebasi YH. Ficus carica and its constituents role in management of diseases. Asian J Pharm Clin Res 2017;10(6):49-53.
9. Oliveira AP, Valentão P, Pereira JA, Silva BM, Tavares F, Andrade PB. Ficus carica L.: Metabolic and biological screening. Food Chem Toxicol 2009;47(11):2841–2846.
10. Jeong WS, Lachance PA. Phytosterols and fatty acids in fig (Ficus carica var. Mission) fruit and tree components. J Food Sci 2001;66. 278-281.
11. Konyalıoğlu S, Sağlam H, Kıvçak B. Alfa Tocopherol, Flavonoid, and Phenol Contents and Antioxidant Activity of Ficus carica Leaves. Pharm Biol 2005;43(8):683-686.
12. Veberic R, Colaric M, Stampar F. Phenolic acids and flavonoids of fig fruit (Ficus carica L.) in the northern Mediterranean region. Food Chem 2008;106(1):153–157.
13. Oliveira AP, Silva LR, de Pinho PG, Gil-Izquierdo A, Valentão P, Silva BM, Pereira, JA., Andrade PB. Volatile profiling of Ficus carica varieties by HS-SPME and GC–IT-MS. Food Chem 2010;123:548-557.
14. Pande G, Akoh CC. Organic acids, antioxidant capacity, phenolic content and lipid characterization of Georgia-grown underutilized fruit crops. Food Chem 2010;120:1067-1075.
15. Çalışkan O, Polat AA. Phytochemical and antioxidant properties of selected fig (Ficus carica L.) accessions from the eastern Mediterranean region of Turkey. Sci Hortic 2011;128;473-478.
16. Slatnar A, Klancar U, Stampar F, Veberic R. Effect of drying of figs (Ficus carica L.) on the contents of sugars, organic acids, and phenolic compounds. J Agric Food Chem 2011;59:11696-11702.
17. Faleh E, Oliveira AP, Valentão P, Ferchichi A., Silva BM, Andrade PB. Influence of Tunisian Ficus carica fruit variability in phenolic profiles and in vitro radical scavenging potential. Braz J Pharmacognosy 2012;22(6):1282-1289.
18. Ercisli S, Tosun M, Karlidag H, Dzubur A, Hadziabulic S, Aliman Y. Color and antioxidant characteristics of some fresh fig (Ficus carica L.) genotypes from Northeastern Turkey. Plant Foods Hum Nutr 2012;67:271-276.
19. Girones-Vilaplana A, Baenas N, Villano, D, Speisky H, Garcia-Viguera C, Moreno, DA. Evaluation of Latin-American fruits rich in phytochemicals with biological effects. J Funct Foods 2014;7:599-608.
20. Takahashi T, Okiura A, Saito KK, Kohno M. Identification of phenylpropanoids in fig (Ficus carica L.) leaves. J Agric Food Chem 2014;62:10076-10083.
21. Weli AM, Al-Blushi AAM, Hossain MA. Evaluation of antioxidant and antimicrobial potential of different leaves crude extracts of Omani Ficus carica against food borne pathogenic bacteria. Asian Pac J Trop Dis 2015;5(1):13-16.
22. Mahmoudi S, Khali M, Benkhaled A, Benamirouche K, Baiti I. Phenolic and flavonoid contents, antioxidant and antimicrobial activities of leaf extracts from ten Algerian Ficus carica L. varieties. Asian Pac J Trop Biomed 2016;6(3):239-245.
23. Shiraishi SC, Kawakami K, Widodo SE, Shiraishi M, Kitazaki M. Organic acid profile in the juice of fig fruits. J Fac Agric Kyushu Univ 1996;41:29–33.
24. Oliveira AP, Silva LR, Andrade PB., Valentão P, Silva BM, Gonçalves RF, Pereira JA, Guedes de Pinho P. Further insight into the latex metabolite profile of Ficus carica. J Agric Food Chem 2010;58:10855–10863.
25. Soni N, Mehta S, Satpathy G, Gupta R. Estimation of nutritional, phytochemical, antioxidant and antibacterial activity of dried fig (Ficus carica). J Pharmacogn Phytochem 2014;3(2):158-165.
26. Sheppard AJ, Pennington JA, Weihrauch JL. Analysis and distribution of vitamin E in vegetable oils and foods. In: Packer L, Fuchs J (ed.). Vitamin E in Health and Disease, New York: Marcel Dekker; 1993. pp. 9–31.
27. Ong ASH. Natural sources of tocotrienols. In: Packer L, Fuchs J (ed.). Vitamin E in Health and Disease. New York: Marcel Dekker; 1993. pp. 3-8.