A mixture of vegetable extracts (chamomile, passionflower, caraway, fennel) and enzymes (beta-galactosidase) for Irritable Bowel Syndrome (IBS): an observational study ("BIOVES")
STUDIO "BIOVES"
Authors
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Giovanni Tomasello
BIONEC DEPARTMENT, University of Palermo, Italy School of Medicine and Surgery
http://orcid.org/0000-0002-3071-822X
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Vincenzo Davide Palumbo
Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo, Palermo, Italy
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Emanuele Sinagra
Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; 4Digestive Endoscopy Service, “G. Giglio” Hospital, Cefalù, Italy
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Margherita Mazzola
Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy - E-mail: giovanni. tomasello@unipa.it; Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
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Agostino Accardo
School of Medicine, University of Palermo, Palermo, Italy
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Andrea Busalacchi
Department of General Surgery and Medical- Surgical Specialties, University of Catania, Catania, Italy
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Antonio Ciulla
Torina Hospital, Palermo, Italy
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Benedetto Di Trapani
Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy; Torina Hospital, Palermo, Italy
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Paolo Pirrotta
Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo, Italy
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Simone Tomasini
Torina Hospital, Palermo, Italy
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Bartolo De Luca
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
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Simona Cusimano
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
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Salvatore Sardo
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
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Giuseppina Di Gaetano
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
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Claudia Corallo
Azienda Sanitaria Provinciale Palermo, Palermo, Italy
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Gianluca Bonetti
School of Medicine, Poland University, Czech Republic
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Monica Pellerone
Kore University, Enna, Italy
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Giulia Tomasello
School of Human and Society Sciences, Kore University, Enna, Italy
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Provvidenza Damiani
A.O.U.P. “P. Giaccone” Hospital University, Palermo, Italy
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Francesco Carini
Department of Experimental Biomedicine and Clinical Neurosciences, University of Palermo, Palermo, Italy
Keywords:
irritable bowel syndrome, gastroenterology, alternative treatments
Abstract
Aims: Irritable bowel syndrome (IBS) is a functional intestinal disorder. This syndrome may creates psychological disorders in patients who are affected and severely limits daily activities and lifestyle. Methods: We investigated the effect of the natural product consisting of chamomile, fennel, caraway, passionflower and melissa (Spasmicol®), on IBS patients. For the study, 187 patients with IBS, enrolled by primary care doctors, were treated with Spasmicol® (Aristeia Farmaceutici s.r.l.), two tablets/daily, for 30 days. At the end of the study, patients were re-evaluated to analyse the effects of therapy. Results: After 30 days, patients showed a marked reduction of symptoms (abdominal pain, abdominal distention, stool habit changes). Conclusions: Due to to the combination of chamomile, fennel, caraway, melissa, passionflower and beta-galactosidase, the product Spasmicol® turned out to be remarkedly effective in treating IBS symptoms.
Author Biography
Giovanni Tomasello, BIONEC DEPARTMENT, University of Palermo, Italy School of Medicine and Surgery
Professore Aggregato MED 18 Chirurgia Generale, Scuola di Medicina e Chirurgia, Università di Palermo.
Section
Original articles
License
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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How to Cite
1.
Tomasello G, Palumbo VD, Sinagra E, Mazzola M, Accardo A, Busalacchi A, et al. A mixture of vegetable extracts (chamomile, passionflower, caraway, fennel) and enzymes (beta-galactosidase) for Irritable Bowel Syndrome (IBS): an observational study ("BIOVES"): STUDIO "BIOVES". Progr Nutr [Internet]. 2018 Sep. 23 [cited 2025 Apr. 13];20(3):526-31. Available from:
https://mattioli1885journals.com/index.php/progressinnutrition/article/view/7574
