Behind the wall: a paleopathological examination of a non-adult subject from the cemetery of Santa Maria Maggiore, Vercelli

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Arianna Vanni
Roberta Fusco


vitamin deficiency, scurvy, nonadults, Santa Maria Maggiore


This study presents the anthropological and paleopathological investigation of  Non-adult#1, an infant recovered from Funerary Unit 12 within the church of Santa Maria Maggiore in Vercelli, Italy. Non-adult#1 exhibited skeletal evidence suggestive of scurvy, characterized by diffuse porosity and new bone deposition in various skeletal elements. Through a comprehensive analysis incorporating macroscopic observations, skeletal measurements and cross-referencing with clinical and paleopathological literature, Non-adult#1 was classified as a probable case of scurvy. The interpretation of Non-adult#1's skeletal remains was further complicated by preservation challenges, incomplete mineralization and the fragmentary nature of the assemblage. Despite these complexities, Non-adult#1's pathology offers valuable insights into the health status and societal conditions of individuals in Modern Era northern Italy. This interdisciplinary approach underscores the importance of integrating archaeological, historical, and bioarchaeological perspectives to elucidate the complexities of past human health and well-being.

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Bennike, P. (1985). Palaeopathology of Danish skeletons. Akademisk Forlag, Copenhagen.
Bettin, S. (2022). Archeologia e antropologia fisica a Santa Maria Maggiore di Vercelli [Corso di Laurea Triennale in Lettere]. Università del Piemonte Orientale.
Blondiaux, G., Blondiaux, J., Secousse, F., Cotten, A., Danze, P. M., & Flipo, R. M. (2002). Rickets and child abuse: the case of a two year old girl from the 4th century in Lisieux (Normandy). International Journal of Osteoarchaeology, 12(3), 209–215.
Brickley, M. B., & Mays, S. (2019). Metabolic Disease. In J.E. Buikstra (Ed), Ortner’s Identification of Pathological Conditions in Human Skeletal Remains, (pp. 531–566). Elsevier Science Publishing Co Inc.
Brickley, M. B., Mays, S., George, M., & Prowse, T. L. (2018). Analysis of patterning in the occurrence of skeletal lesions used as indicators of vitamin D deficiency in subadult and adult skeletal remains. International Journal of Paleopathology, 23, 43–53.
Brickley, M. B., Moffat, T., & Watamaniuk, L. (2014). Biocultural perspectives of vitamin D deficiency in the past. Journal of Anthropological Archaeology, 36(1), 48–59.
Brickley, M., & Ives, R. (2006). Skeletal manifestations of infantile scurvy. American Journal of Physical Anthropology, 129(2), 163–172.
Brickley, M., Ives, R., & Mays, S. (2020). The Bioarchaeology of Metabolic Bone Disease. Academic Press, Cambridge.
Buikstra, J. E. (2019). Ortner’s Identification of Pathological Conditions in Human Skeletal Remains. Academic Press, Cambridge.
Buikstra, J. E., & Ubelaker, D. (1994). Standards for data collection from human skeletal remains. . Arkansas Archeological Survey, Fayetteville.
Caldano, S. (2019). Un cantiere per un capitolo canonicale di prestigio: Santa Maria Maggiore di Vercelli nel XII secolo. Arte Lombarda, 186/187(2–3), 71–84.
Clevis, H., & Constandse-Westermann, T. S. (1992). De doden vertellen : opgraving in de Broerenkerk te Zwolle 1987-88. Stichting Archeologie Ijssel, Kampen.
de Boer, H. H. H., & Van der Merwe, A. E. L. (2016). Diagnostic dry bone histology in human paleopathology. Clinical Anatomy, 29(7), 831–843.
D’Ortenzio, L., Ribot, I., Raguin, E., Schattmann, A., Bertrand, B., Kahlon, B., & Brickley, M. (2016). The rachitic tooth: A histological examination. Journal of Archaeological Science, 74, 152–163.
Ellis, M. A. B. (2014). A Disciplined Childhood in Nineteenth-Century New York City: A Social Bioarchaeology of the Subadults of the Spring Street Presbyterian Church. Tracing Childhood, 139–156.
Fusco, R., Messina, C., Tesi, C., & Vanni, A. (2023). “Capta est ne malitia mutaret intelletum eius.” Study on a natural mummy from an underground cemetery (18-19th century). Medicina Historica, 7(2), e2023044. Retrieved from
Garanzini, F., Destefanis, E., Fusco, R., & Licata, M. (2023). Vercelli. Chiesa concattedrale di S. Maria Maggiore. Indagini bioarcheologiche. Notiziario Della Soprintendenza Archeologia Belle Arti e Paesaggio per Le Province Di Biella Novara Verbano-Cusio-Ossola e Vercelli, 7, 114–118.
Geber, J., & Murphy, E. (2012). Scurvy in the Great Irish Famine: Evidence of Vitamin C Deficiency From a Mid-19th Century Skeletal Population. American Journal of Physical Anthropology, 148(4), 512–524.
Giuffra, V., Vitiello, A., Caramella, D., Fornaciari, A., Giustini, D., & Fornaciari, G. (2015). Rickets in a High Social Class of Renaissance Italy: The Medici Children. International Journal of Osteoarchaeology, 25(5), 608–624.
Guy, H., Masset, C., & Baud, C. A. (1997). Infant taphonomy. International Journal of Osteoarchaeology, 7, 221–229.
Henderson, C., Evans-Lacko, S., & Thornicroft, G. (2013). Mental Illness Stigma, Help Seeking, and Public Health Programs. American Journal of Public Health, 103(5), 777–780.
Larentis, O., Licata, M., Tonina, E., & Pangrazzi, C. (2023). Probable micronutrient deficiency diseases in a rural community. The nonadults of Mary’s Nativity church, 16th century, Trentino Alto-Adige, Italy. Journal of Archaeological Science: Reports, 47, 103774.
Larentis, O., Tonina, E., Iorio, S., Gorini, I., & Licata, M. (2020). Osteological evidence of metabolic diseases from a post medieval North Italy archaeological site. Journal of Maternal-Fetal and Neonatal Medicine, 33(16), 2735–2742.
Lewis, D., Carpenter, C., Evans, A., & Thomas, P. (2006). Rickets and Scurvy presenting in a Child as apparent Non Accidental Injury. The Internet Journal of Orthopedic Surgery, 4(2).
Licata, M., Tesi, C., Larentis, O., Destefanis, E., Garanzini, F., Ciliberti, R., & Fusco, R. (2024). Elongated styloid process of an autopsied skull from the Cemetery of Santa Maria Maggiore in Vercelli, 18th–19th century (Piedmont, northern Italy). Anthropologischer Anzeiger, 81(2), 209–218.
Littleton, J. (1998). A middle eastern paradox: rickets in skeletons from Bahrain. Journal of Paleopathology, 10, 13–30.
Magiorkinis, E., Beloukas, A., & Diamantis, A. (2011). Scurvy: Past, present and future. European Journal of Internal Medicine, 22(2), 147–152.
Maiyegun, S. O., Malek, A. H., Devarajan, L. V., & Dahniya, M. H. (2002). Severe congenital rickets secondary to maternal hypovitaminosis D: A case report. Annals of Tropical Paediatrics, 22(2), 191–195.
Maresh, M. M. (1970). Measurements from Roentgenograms. In R. W. McCammon (Ed.), Human Growth and Development (pp. 157–200). C.C. Thomas, Springfield.
Mays, S. (2008). A likely case of scurvy from early Bronze Age Britain. International Journal of Osteoarchaeology, 18(2), 178–187.
Mays, S. (2014). The palaeopathology of scurvy in Europe. International Journal of Paleopathology, 5, 55–62.
Mays, S., Brickley, M., & Ives, R. (2006). Skeletal manifestation of rickets in infants and young children in a historic population from England. American Journal of Physical Anthropology, 129(3), 362–374.
Meyer, A. (2016). Assessment of diet and recognition of nutritional deficiencies in paleopathological studies: A review. Clinical Anatomy, 29(7), 862–869.
Minozzi, S., & Canci, A. (2015). Archeologia dei resti umani. Dallo scavo al laboratorio. Carocci Editore, Roma.
Novak, M., Vyroubal, V., Krncevic, Z., Petrinec, M., Howcroft, R., Pinhasi, R., & Slaus, M. (2018). Assessing childhood stress in early mediaeval Croatia by using multiple lines of inquiry. In Anthropologischer Anzeiger, 75(2), 155–167.
Ortner, D. (2003). Identification of pathological conditions in human skeletal remains. Academic Press, Cambridge.
Ortner, D., & Ericksen, M. F. (1997). Bone changes in the human skull probably resulting from scurvy in infancy and childhood. International Journal of Osteoarchaeology, 7, 212–220.
Ortner, D. J., Butler, W., Cafarella, J., & Milligan, L. (2001). Evidence of probable scurvy in subadults from archeological sites in North America. American Journal of Physical Anthropology, 114(4), 343–351.
Ortner, D. J., Kimmerle, E. H., & Diez, M. (1999). Probable Evidence of Scurvy in Subadults From Archeological Sites in Peru. American Journal of Physical Anthropology, 108, 321–331.
Ortner, D., & Mays, S. (1998). Dry-bone manifestations of rickets in infancy and early childhood. International Journal of Osteoarchaeology, 8, 45–55.
Resnick, D., & Niwayama, G. (1988). Diagnosis of Bone and Joint Disorders. Saunders, Philadelphia.
Ribot, I., & Roberts, C. (1996). A Study of Non-specific Stress Indicators and Skeletal Growth in Two Mediaeval Subadult Populations. Journal of Archaeological Science, 23(1), 67–79.
Saunders, S., Hoppa, R., & Southern, R. (1993). Diaphyseal growth in a nineteenth century skeletal sample of subadults from St Thomas’ church, Belleville, Ontario. International Journal of Osteoarchaeology, 3(4), 265–281.
Schattmann, A., Bertrand, B., Vatteoni, S., & Brickley, M. (2016). Approaches to co-occurrence: Scurvy and rickets in infants and young children of 16-18th century Douai, France. International Journal of Paleopathology, 12, 63–75.
Scheuer, Louise., & Black, S. M. (2000). Developmental juvenile osteology. Academic Press, Cambridge.
Snoddy, A. M. E., Buckley, H. R., Elliott, G. E., Standen, V. G., Arriaza, B. T., & Halcrow, S. E. (2018). Macroscopic features of scurvy in human skeletal remains: A literature synthesis and diagnostic guide. American Journal of Physical Anthropology, 167(4), 876–895.
Sommo, G. (2008). Vercelli e la memoria dell’antico. Schede e documenti per un approccio alla storia ed ai problemi dell’archeologia, della tutela e conservazione in un centro della provincia piemontese. Edizione elettronica Gruppo Archeologico Vercellese.
Stark, R. J. (2014). A proposed framework for the study of paleopathological cases of subadult scurvy. International Journal of Paleopathology, 5, 18–26.
Thaler, R., Khani, F., Sturmlechner, I., Dehghani, S. S., Denbeigh, J. M., Zhou, X., Pichurin, O., Dudakovic, A., Jerez, S. S., Zhong, J., Lee, J. H., Natarajan, R., Kalajzic, I., Jiang, Y. hui, Deyle, D. R., Paschalis, E. P., Misof, B. M., Ordog, T., & van Wijnen, A. J. (2022). Vitamin C epigenetically controls osteogenesis and bone mineralization. Nature Communications, 13(1), 5883.
Tibaldeschi G. (1996). La Chiesa di S. Maria Maggiore di Vercelli e l’Assunzione di Paolo Borroni. Bollettino Storico Vercellese, 2, 131–150.
Trapani, S., Rubino, C., Indolfi, G., & Lionetti, P. (2022). A Narrative Review on Pediatric Scurvy: The Last Twenty Years. In Nutrients, 14(3), 684.
Ubelaker, D. H. (1989). Human Skeletal Remains: Excavation, Analysis, lnterpretation. Taraxacum.
Vanni, A., & Fusco, R. (2023). Companions in eternity. The historical practice of burying pets. In Journal of Bioarchaeological Research, 1(3), e2023023. Retrieved from
Vanni, A., Fusco, R., Tesi, C., & Licata, M. (2024). Autopsy or anatomical dissection? Comparative analysis of an osteoarchaeological sample from an 18-19th century hypogeal cemetery (northern Italy). Journal of Archaeological Science: Reports, 54, 104418.
Veselka, B., Hoogland, M. L. P., & Waters-Rist, A. L. (2015). Rural Rickets: vitamin D deficiency in a post-medieval farming community from the Netherlands. International Journal of Osteoarchaeology, 25, 665–675.
Zuckerman, M. K., Garofalo, E. M., Frohlich, B., & Ortner, D. J. (2014). Anemia or scurvy: A pilot study on differential diagnosis of porous and hyperostotic lesions using differential cranial vault thickness in subadult humans. International Journal of Paleopathology, 5, 27–33.