The effect of long term exercise on leptin levels in adolescent wrestlers
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Keywords
Exercise, Leptin, Adolescent, Wrestlers, Long term exercise
Abstract
Study Objectives: The implication of leptin in physical exercise and during its recovery is still unclear. The aim of this study was to examine the effect of eight-month regular well-developed wrestling training in male adolescents on leptin levels, where metabolic and endocrine changes are important. Methods: The sample for this study comprised 69 volunteering male individual subjects who were divided into two different groups. The training program was applied to the 49 male adolescent wrestling group age of 13–15 years (14.4±10.61 years), for 90-120 minutes/day for five days a week during the eight months. The control group consisted of 20 males age between 13–15 years (14.05±0.76 years) who did not receive any planned exercise sessions. Data about the anthropometric and metabolic characteristics including age, body weight, height, body mass index (BMI), waist circumferences, and leptin were obtained. Data were analyzed with the SPSS for Windows 21.0 software. Mann Whitney U Test was used to comparison of independent groups, Wilcoxon Signed Rank Test and Paired Samples t-Test were used to comparison of measurement times, results of analysis were evaluated with 95% confidence interval. Results: There were statistical significantly increase in height, weight, waist circumference, and BMI results of male adolescent wrestlers who did wrestling training for months (p<0.05). No statistical change was found between leptin levels (p>0.05), while leptin levels decreased significantly with puberty (p<0.05). Conclusion: Although some studies indicate that there is a strong relationship between BMI and leptin level, such a relationship was not found in our study. This situation is thought to be caused by physiological changes that are important and effective in adolescence.
References
2. Bouassida A, Zalleg D, Bouassida S, et al. Leptin, its implication in physical exercise and training: a short review. J Sports Sci Med. 2006; 5(2): 172-181.
3. Kelly T, Yang W, Chen C, Reynolds K, He J. Global burden of obesity in 2005 and projections to 2030. Int J Obes. 2008; 32(9): 1431–7.
4. Benjamin RM. The Surgeon General’s vision for a healthy and fit nation. Public Health Rep. 2010; 125(4): 514.
5. Spruijt-Metz D. Etiology, Treatment and Prevention of Obesity in Childhood and Adolescence: A Decade in Review. J Res Adolesc. 2011; 21(1): 129-152.
6. Meldrum DR, Morris MA, Gambone JC. Obesity pandemic: causes, consequences, and solutions-but do we have the will?. Fertil Steril. 2017; 107: 833–9.
7. Reilly SM, Saltiel AR. Adapting to obesity with adipose tissue inflammation. Nat Rev Endocrinol. 2017; 13: 633-43.
8. Klok MD, Jakobsdottir S, Drent ML. The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review. Obes Rev. 2007; 8(1): 21-34.
9. Hamrick MW. Role of the cytokine-like hormone leptin in muscle-bone crosstalk with aging. J Bone Metab. 2017; 24: 1-8.
10. Guerra B, Santana A, Fuentes T. et al. Leptin receptors in human skeletal muscle. J Appl Physiol. 2007; 102: 1786–92.
11. Sinha MK, Sturis J, Ohannesian J. et al. Ultradian oscillations of leptin secretion in humans Biochem Biophys Res Commun. 1996; 228: 733-738.
12. Ducy P, Amling M, Takeda S. et al. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell. 2000; 100: 197-207.
13. Turner RT, Kalra SP, Wong CP. et al. Peripheral leptin regulates bone formation. J Bone Miner Res. 2013; 28; 22-34.
14. Galic S, Oakhill JS, Steinberg GR. Adipose tissue as an endocrine organ. Mol Cell Endocrinol. 2010; 316(2): 129–39.
15. Hilton LK, Loucks AB. Low energy availability, not exercise stress, suppresses the diurnal rhythm of leptin in healthy young women. Am J Physiol Endocrinol Metab. 2000; 278(1): E43-9.
16. Marshall WA, Tanner JM. Variations in the pattern of pubertal changes in boys. Arch Dis Child 1970; 45: 13-23.
17. Alzamil H, Aldokhi L, Habib SS. Physical Fitness and Its Relationship to Plasma Leptin, Leptin Soluble Receptor, and Free Leptin Index in a Saudi Population: A Comparison Between Diabetic and Non-Diabetic Individuals. Medical science monitor basic research. 2018; 24: 113-119.
18. Plonka M, Toton-Morys A, Adamski P, Suder A, Bielanski W, Dobrzanska MJ, Kaminska A, Piorecka B, Glodzik J. J Physiol Pharmacol. 2011; 62(6): 647-56.
19. Jiménez-Pavón D, Ortega FB, Artero EG, et al. HELENA Study Group. Physical activity, fitness, and serum leptin concentrations in adolescents. J Pediatr. 2012; 160(4): 598–603.
20. Miyatake N, Murakami H, Kawakami R. et al.. Circulating leptin levels are associated with physical activity or physical fitness in Japanese. Environmental health and preventive medicine. 2014; 19(5): 362-366.
21. Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactivity-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996; 334: 292-5.
22. Hirose H, Saito I, Kawai T, et al. Serum leptin level: possible association with hematopoiesis in adolescents, independent of body mass index and serum insulin. Clin Sci (Lond). 1998; 94: 633–6.
23. Grontved A, Steene-Johannessen J, Kynde I, et al. Association between plasma leptin and blood pressure in two population-based samples of children and adolescents. J Hypertens. 2011; 29: 1093–100.
24. Fujita Y, Kouda K, Ohara K. ae al. Leptin mediates the relationship between fat mass and blood pressure: The Hamamatsu School-based health study. Medicine. 2019; 98(12): e14934.
25. Bouassida A, Chamari K, Zaouali M, et al. Review on leptin and adiponectin responses and adaptations to acute and chronic exercise. British Journal of Sports Medicine. 2010; 44: 620-630.
26. Lin H, Hu M, Yan Y. et al. The effect of exercise on adiponectin and leptin levels in overweight or obese subjects: a meta-analysis of randomized controlled trials. Sport Sci Health. 2017; 13. 303-314.
27. de Salles BF, Simao R, Fleck SJ, et al. Effects of resistance training on cytokines. Int J Sports Med. 2010; 31: 441-450.
28. Bird L. Exercise lowers leptin and leukocytosis. Nat Rev Immunol. 2020; 20(1): 2-3.
29. Kraemer RR, Aboudehen KS, Carruth AK. et al. Adiponectin responses to continuous and progressively intense intermittent exercise. Med Sci Sports Exerc. 2003; 35: 1320-1325.
30. Hoogeveen AR, Zonderland ML. Relationships between testosterone, cortisol and performance in professional cyclists. Int J Sports Med. 1996; 17: 423-428.
31. Pilcova R, Sulcova J, Tepesi M. et al. Leptin levels in obese children: effects of gender, weight reduction and androgens. Physiol Res. 2003; 52(1): 53-60.
32. Tsolakis C, Vagenas G, Dessypris A. Growth and anabolic hormones, leptin, and neuromuscular performance in moderately trained prepubescent athletes and untrained boys. J Strength Cond Res. 2003; 17: 40-46.
33. Jones TE, Basilio JL, Brophy PM. et al. Long-term exercise training in overweight adolescents improves plasma peptide YY and resist in. Obesity (Silver Spring, Md.). 2009; 17(6): 1189-1195.
34. Sudi KM, Gallistl S, Borkenstein MH et al. Effects of weight loss on leptin, sex hormones, and measures of adiposity in obese children Endocrine 2001; 14: 429 - 435.
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