Investigation of thiol/disulfide balance and IMA value before and after training in elite female weightlifters
Main Article Content
Keywords
Weightlifting, oxidative stress, Ischemia-Modified Albumin, Thiol/Disulfide
Abstract
Study Objectives: Doing exercise has certain acute and chronic effects on the body. As part of the metabolic processes, the cells in our body constantly produce free radicals and reactive oxygen species (ROS) during aerobic cellular metabolism, while the antioxidant defense system tries to adapt to this condition. Any change in this balanced state in favor of ROS is considered oxidative stress. Thiol-disulfide balance is a unique, easy, and new method for determining oxidative stress. Ischemia-Modified Albumin (IMA) tissue ischemia is accepted as a new indicator specifically revealing oxidative stress. In the accessible literature in the sports sciences field, no previous studies have been found on the thiol/disulfide balance and IMA value, which have recently been discovered to be among the biomarkers of oxidative stress. Therefore, it was aimed to investigate the thiol/disulfide balance and IMA value in elite female weightlifters before and after training. Methods: The study group of this research was comprised of elite female weightlifters (N= 12) who participated in competitions on behalf of the Turkish National Weightlifting Team, had a training history of at least 5 years, and who were training 5 days a week and above. Oxidative stress parameters (native-thiol, total thiol, disulfide values, and calculated parameters disulfide / native-thiol, disulfide / total thiol and natural thiol / total thiol ratios) and IMA levels of these athletes were evaluated before the training (Group-I) and after the training (Group-II). Results: It was determined that there was no statistically significant difference between Group I and II. Conclusion: It can be mentioned that elite female weightlifters in the study provided metabolic adaptation to the training they performed, and the compensation of antioxidant defense was good. This was interpreted that the participants could continue to the next level of heavier training.
References
2. Anastasia P, Ioannis SV, Laskarina-Maria K, et al. Comparison of the short-term oxidative stress response in national league basketball and soccer adolescent athletes. Angiology 2013; 65(7): 624-629.
3. Arsic A, Vucic V, Glibetic M, et al. Redox balance in elite female athletes: Differences based on sport types. J Sports Med Phys Fitness January-February (2016); 56(1-2): 1-8.
4. Çelik A, Varol R, Onat T, et al. Akut egzersizin futbolcularda antioksidan sistem parametrelerine etkisi. SPORMETRE Beden Eğitimi ve Spor Bilimleri Dergisi 2007; 4: 167-172.
5. Hadžović-Džuvo A, Valjevac A, Lepara O, et al. Oxidative stress status in elite athletes engaged in different sport disciplines. Bosnian Journal of Basic Medical Sciences 2014; 14(2): 56–62.
6. Pingitore A, Giuseppina PPL, Francesca M, et al. Exercise and oxidative stress: Potential effects of antioxidant dietary strategies in sports. Nutrition 2015; 31(7-8): 916–922.
7. Gul M, Bugday MS, Erel O. 2018. Thiol-disulphide homoeostasis as an oxidative stress marker in men with varicocele. Andrologia 2018; 50(4): e12982.
8. Erel O, Neselioglu S. A novel and automated assay for thiol/disulphide homeostasis. Clinical Biochemistry 2014; 47(18): 326-332. DOI: 10.1016/j.clinbiochem.2014.09.026.
9. Dahiya K, Kumar R, Dhankhar R, et al. Status of ischemia modified albumin in athletes before and after moderate exercise. The Open Biomarkers Journal 2018; 8(1): 42-46.
10. Memmedov H. boks ve kickboks spor müsabakalarının travmatik beyin hasarı oluşturma riskinin laboratuvar açısından değerlendirilmesi. Atatürk Üniversitesi Sağlık Bilimleri Enstitüsü Tıbbi Biyokimya Anabilim Dalı Yüksek Lisans Tezi, 2014.
11. Ammar A, Turki M, Hammouda O, et al. Effects of pomegranate juice supplementation on oxidative stress biomarkers following weightlifting exercise. Nutrients 2017; 9(8): 819. http://doi.org/10.3390/nu9080819.
12. Bar-Or D, Lau E, Winkler JV. A novel assay for cobalt-albumin binding and its potential as a marker for myocardial ischemia: A preliminary report. J Emerg Med 2000; 19: 311-315.
13. Gol M, Özkaya B, Yildirim C, et al. Regular exercise, overweight/obesity and sedentary lifestyle cause adaptive changes in thiol–disulfide homeostasis. An Acad Bras Cienc 2019; 91(2): 1-10.
14. McLeay Y, Stannard S, Houltham S, et al. Dietary thiols in exercise: Oxidative stress defence, exercise performance, and adaptation. Journal of the International Society of Sports Nutrition 2017; 14(12): 2-8.
15. Atabek HÇ. Egzersiz ve Oksidatif Stres: Direnç Egzersizlerin Etkisi. Türkiye Klinikleri Spor Bilimleri Dergisi 2011; 3(2): 92-100.
16. Simioni C, Zauli G, Martelli AM, et al. Oxidative stress: Role of physical exercise and antioxidant nutraceuticals in adulthood and aging. Oncotarget 2018; 9(24): 17181-17198.
17. Kürkçü R, Çakmak A, Zeyrek D. (2012). Taekwondo antrenmanlarının çocuklarda oksidatif stres üzerine etkisi. Erciyes Med J, 34(1): 7-9.
18. Chaki B, Pal S, Chattopadhyay S, et al. High-intensity exercise-induced oxidative stress in sedentary pre-pubertal & post-pubertal boys: A comparative study. Indian J Med Res 2019; 150(2): 167-174.
19. Uchiyama S, Tsukamoto H, Yoshimura S, et al. Relationship between oxidative stress in muscle tissue and weight-lifting-induced muscle damage. Pflügers Archiv-European Journal of Physiology 2006; 452(1): 109-116.
20. Çolak T, Bamaç B, Çolak S, et al. The influence of a single bout of wrestling exercise on serum levels of ischemia-modified albumin. J Exerc Sci Fit 2010; 8(2) 67–72.
21. Duman, C, Çolak, T, Bamaç, B, et al. Ischemia-modified albumin levels in professional male soccer players before and after training. Marmara Medical Journal 2013; 26(1): 21-24.
22. Erenler AK, Yardan T, Kati C, et al. Role of ischemia-modified albumin in clinical practice. J Lab Med 2015; 39(4): 241–247.
Article Sidebar
Article Details
How to Cite
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Transfer of Copyright and Permission to Reproduce Parts of Published Papers.
Authors retain the copyright for their published work. No formal permission will be required to reproduce parts (tables or illustrations) of published papers, provided the source is quoted appropriately and reproduction has no commercial intent. Reproductions with commercial intent will require written permission and payment of royalties.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
