Resorbable Purified Porcine Skin Gelatin Cross-Linked with Glutaraldehyde Spheres for Preoperative Embolization of Carotid Body Paraganglioma

Resorbable Purified Porcine Skin Gelatin Cross-Linked with Glutaraldehyde Spheres for Preoperative Embolization of Carotid Body Paraganglioma

Authors

  • Sophia Hohenstatt Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico https://orcid.org/0000-0003-0951-3948
  • Salvatore Alessio Angileri Fondazione IRCCS ospedale Maggiore Policlinico Milano
  • Giuseppe Granata Postgraduate School in Radiodiagnostic, Facoltà di Medicina e Chirurgia, Università degli Studi di Milano
  • Aldo Paolucci Unit of Radiology, IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan
  • Anna Maria Ierardi Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
  • Gianpaolo Carrafiello Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
  • Ruggiero Curci Ospedale Maggiore di Lodi - ASST Lodi

Keywords:

paraganglioma, embolization, chemodectoma, interventional radiology, microspheres, high vascular tumor

Abstract

Chemodectomas are rare neuroendocrine tumors that typically arise at the carotid bifurcation and progressively englobe the internal and external carotid artery. Surgical asportation of the capsulated mass is the elective treatment. Pre-procedural embolization of this high vascular tumors is highly recommended because it has shown to improve surgical outcome by reducing both, mean blood loss and total operation time. Many different embolization techniques have been described in literature. In the here presented case we opted for an endovascular approach using resorbable purified porcine skin gelatin cross-linked with glutaraldehyde microspheres (Optisphere - MEDTRONIC) as an embolic agent. These turned out to be very safe and effective in improving surgical outcome by reducing operative blood loss and thus reducing treatment-related morbidity.

References

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Published

30-04-2021

Issue

Section

Case Reports: Oncology and Hematology

How to Cite

1.
Resorbable Purified Porcine Skin Gelatin Cross-Linked with Glutaraldehyde Spheres for Preoperative Embolization of Carotid Body Paraganglioma. Acta Biomed [Internet]. 2021 Apr. 30 [cited 2024 Jun. 30];92(S1):e2021159. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/9488