Chronic urticaria and drug hypersensitivity in children

Carlo Mastrorilli; Roberto Bernardini; Lucia Liotti; Fabrizio Franceschini; Giuseppe Crisafulli; Silvia Caimmi; Paolo Bottau; Francesca Mori; Fabio Cardinale; Francesca Saretta; Giovanni Simeone; Marcello Bergamini; Carlo Caffarelli

doi:10.23750/abm.v90i3-S.8166

Chronic urticaria and drug hypersensitivity in children

Authors

Carlo Mastrorilli Clinica Pediatrica, Dipartimento di Medicina e Chirurgia, Azienda Ospedaliero-Universitaria, Università di Parma, Italy
Roberto Bernardini Pediatric Unit, “San Giuseppe” Hospital, Empoli, Italy
Lucia Liotti Department of Pediatrics, Senigallia Hospital, Senigallia, Italy
Fabrizio Franceschini UOC Pediatria, Azienda Ospedaliero-Universitaria “Ospedali Riuniti”, Ancona, Italy
Giuseppe Crisafulli UO Allergologia, Dipartimento di Pediatria, Università di Messina, Italy
Silvia Caimmi Pediatric Clinic, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
Paolo Bottau Pediatric and Neonatology Unit, Imola Hospital, Imola (BO), Italy
Francesca Mori Allergy Unit, Department of Pediatric Medicine, Anna Meyer Children’s University Hospital, Florence, Italy
Fabio Cardinale UOC di Pediatria, Azienda Ospedaliera-Universitaria “Consorziale-Policlinico”, Ospedale Pediatrico Giovanni XXIII, Bari, Italy
Francesca Saretta Pediatric Department, AAS2 Bassa Friulana-Isontina, Palmanova-Latisana, Italy; Pediatric Allergy Unit, Department of Medicine, Udine, Italy
Giovanni Simeone Primary care Pediatrician, Local Health Unit of Brindisi, Brindisi, Italy
Marcello Bergamini Generalist Pediatrician, Local Health Unit of Ferrara, Ferrara, Italy
Carlo Caffarelli Clinica Pediatrica, Dipartimento di Medicina e Chirurgia, Azienda Ospedaliero-Universitaria, Università di Parma, Italy

DOI: https://doi.org/10.23750/abm.v90i3-S.8166

Keywords:

drug hypersensitivity reactions, children, urticaria, skin test, specific IgE, basophil activation test, drug provocation test

Abstract

The cause of chronic urticaria remains often elusive. The association between chronic urticaria and intake of medications have been reported in children. However, the causative role of drugs has been rarely ascertained by onset of symptoms on drug provocation test. Chronic urticaria can be mediated by immunologic and nonimmunologic mechanisms. The diagnostic work-up of chronic urticaria includes a comprehensive evaluation of triggering factors such as drugs. A diagnosis is necessary in order to permit a safely administration of drugs in children with chronic urticaria.

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Published

29-01-2019

Issue

Vol. 90 No. 3-S (2019): Advances in pediatric drug allergy - Guest Editor: Carlo Caffarelli

Section

REVIEWS

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

Mastrorilli C, Bernardini R, Liotti L, et al. Chronic urticaria and drug hypersensitivity in children. Acta Biomed. 2019;90(3-S):61-65. doi:10.23750/abm.v90i3-S.8166

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