Respiratory function in subjects with Chronic Obstructive Pulmonary Disease (COPD) and atmospheric pollution in the city of Parma. Preliminary analysis

Abstract

A hospital case record study was carried out enlisting urgently hospitalized subjects for chronic obstructive pulmonary disease (COPD) in order to study the percentage values variations of Vital Capacity (VC), Forced Vital Capacity (FVC) and maximum expiratory volume in 1 second (FEV1) based on atmospheric pollution trend in Parma city evaluated by PM10, NO2 and O3 concentrations. The results showed an association only between PM10 and hospitalizations for COPD with statistically significant differences between PM10 concentrations assessed 3-4 days before hospitalizations of the study subjects and the ones established in the days without any hospitalization. The regression analysis between PM10 and respiratory function concerning PM10 concentration at 24, 48, 72, 96 hours before the hospitalization showed significant association between FVC% and FEV1% and PM10 concentrations at 96 hours. The calculated Odd Ratio resulted equal to 1,016 (L.C. 1,001-1,032) which corresponds to an increase of hospitalization probability for COPD equal to 1,6% for PM10 increment unit.