Effectiveness of treatment with surfactant in premature infants with respiratory failure and pulmonary infection

Effectiveness of treatment with surfactant in premature infants with respiratory failure and pulmonary infection

Authors

  • G. Vento
  • M. Tana
  • C. Tirone, et al.

Keywords:

Surfactant, pneumonia, premature nonates

Abstract

Introduction: Surfactant inactivation is present in neonatal pneumonia. Materials and Methods: One hundred thirty-nine preterm babies with BirthWeight (BW) ≤ 1250 grams were studied and subdivided in two groups: RDS Group, with a diagnosis of “simple” RDS (N 80) and RDS with Pneumonia Group, consisting of babies with a diagnosis of RDS and a positive BALF culture in the first 24-48 h of life (N 59). Outcomes: Surfactant administration seems less effective in the latter group, because a significantly higher number of infants needed a second dose of surfactant, compared to the patients suffering from RDS alone.

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Published

01-07-2012

Issue

Section

Session 2 – Exogenous surfactant in neonatology

How to Cite

1.
Vento G, Tana M, Tirone, et al. C. Effectiveness of treatment with surfactant in premature infants with respiratory failure and pulmonary infection. Acta Biomed [Internet]. 2012 Jul. 1 [cited 2024 Jul. 27];83(1):36-9. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/2362