Meniscal scaffold implantation in post meniscectomy syndrome results in clinical and radiological outcomes comparable to primary subtotal meniscectomy in patients without post meniscectomy syndrome

Meniscal scaffold implantation in post meniscectomy syndrome results in clinical and radiological outcomes comparable to primary subtotal meniscectomy in patients without post meniscectomy syndrome

Authors

  • Alessio Maione U.O.C. 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy
  • Martina Ricci U.O.C. 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy
  • Sofia Perfetti 2 Scuola Di Specializzazione in Ortopedia e Traumatologia, Università Degli Studi Di Milano, Via Festa del Perdono 7, 20122 Milan, Italy
  • Francesco Poggioli ASST Papa Giovanni XXIII Bergamo
  • Filippo Calanna U.O.C. 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy
  • Marco Puce 2 Scuola Di Specializzazione in Ortopedia e Traumatologia, Università Degli Studi Di Milano, Via Festa del Perdono 7, 20122 Milan, Italy
  • Eva Usellini U.O.C. 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy
  • Pietro Simone Randelli U.O.C. 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy
  • Massimo Berruto U.O.C. 1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy

Keywords:

Knee, meniscal scaffold, meniscectomy, arthroscopy, post meniscectomy syndrome

Abstract

Background and aim: The aim of the study was to assess clinical and radiological outcomes among patients who underwent scaffold implantation after post meniscectomy syndrome (scaffold group) comparing them with patients undergoing primary subtotal meniscectomy (primary subtotal meniscectomy group) without post meniscectomy syndrome at a minimum of 3 years of follow-up. Moreover, the morphology of the meniscal implant was verified by MRI at the last follow-up. Methods: 24 patients were enrolled (age, 37 ± 12.2 years) and two groups of 12 patients were created (scaffold and primary subtotal meniscectomy). Data were collected before surgery, at 12 months and at the last follow-up (min 3 years - max 13 years). Clinical and radiological outcomes (Subjective IKDC score, VAS, Tegner scale, physical examination, Kellgren-Lawrence classification) were collected. MRI images were analyzed according to the Genovese classification. Results: Both groups showed an improvement in knee function at the last follow-up. No differences were recorded in terms of pain reduction at 1 year, while subtotal meniscectomy showed a significantly lower VAS score at the last follow-up. Both groups showed a significant progression of knee osteoarthritis at the last follow-up. No patient showed a completely reabsorbed scaffold. Conclusions: The ActifitTM polyurethane implant demonstrated good clinical and radiological results in patients with symptomatic post meniscectomy syndrome at final follow-up. However IKDC score and VAS showed inferior clinical results compared to those of primary subtotal meniscectomy.

References

Mow VC, Arnoczky SP. Knee Meniscus: Basic and Clinical Foundations. Ann Arbor: Raven Pr 1992

Shoemaker SC, Markolf KL. The role of the meniscus in the anterior-posterior stability of the loaded anterior cruciate-deficient knee. Effects of partial versus total excision. J Bone Joint Surg Am 1986; 68(1):71-9

Walker PS, Erkman MJ. The role of the menisci in force transmission across the knee. Clin Orthop Relat Res 1975;109:184-192

Bansal S, Floyd ER, A Kowalski M, Aikman E, Elrod P, Burkey K et al. Meniscal repair: The current state and recent advances in augmentation. J Orthop Res 2021;39(7):1368-1382

Novaretti JV, Lian J, Patel NK, Chan CK, Cohen M, Musahl V. Partial Lateral Meniscectomy Affects Knee Stability Even in Anterior Cruciate Ligament-Intact Knees. J Bone Joint Surg Am 2020;1;102(7):567-573

Beaufils P, Pujol N. Management of traumatic meniscal tear and degenerative meniscal lesions. Save the meniscus. Orthop Traumatol Surg Res 2017;103(8S):S237-S244

Seil R, Becker R. Time for a paradigm change in meniscal repair: save the meniscus! Knee Surg Sports Traumatol Arthrosc 2016;24(5):1421-3

Spencer SJ, Saithna A, Carmont MR, Dhillon MS, Thompson P, Spalding T. Meniscal scaffolds: early experience and review of the literature. Knee 2012;19(6):760-5

Li W, Pan J, Li J, Guo J, Zeng C, Xie D. Clinical application of polyurethane meniscal scaffold: A meta-analysis. J Orthop. 2021;24:173-181

Reale D, Lucidi GA, Grassi A, Poggi A, Filardo G, Zaffagnini S. A Comparison Between Polyurethane and Collagen Meniscal Scaffold for Partial Meniscal Defects: Similar Positive Clinical Results at a Mean of 10 Years of Follow-Up. Arthroscopy 2022;38(4):1279-1287

Reale D, Previtali D, Andriolo L, Grassi A, Candrian C, Zaffagnini S. No differences in clinical outcome between CMI and Actifit meniscal scaffolds: a systematic review and meta-analysis. Knee Surg Sports Traumatol Arthrosc 2022;30(1):328-348

Collins NJ, Misra D, Felson DT, Crossley KM, Roos EM. Measures of knee function: International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Form, Knee Injury and Osteoarthritis Outcome Score (KOOS), Knee Injury and Osteoarthritis Outcome Score Physical Function Short Form (KOOS-PS), Knee Outcome Survey Activities of Daily Living Scale (KOS-ADL), Lysholm Knee Scoring Scale, Oxford Knee Score (OKS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Activity Rating Scale (ARS), and Tegner Activity Score (TAS). Arthritis Care Res 2011; 63 Suppl 11:S208-228

Karcioglu O, Topacoglu H, Dikme O, Dikme O. A systematic review of the pain scales in adults: Which to use? Am J Emerg Med 2018; 36(4):707–14

Kellgren JH, Lawrence JS. Radiological Assessment of Osteo-Arthrosis. Ann Rheum Dis 1957; 16(4):494–502

Kohn MD, Sassoon AA, Fernando ND. Classifications in Brief: Kellgren-Lawrence Classification of Osteoarthritis. Clin Orthop Relat Res 2016;474(8):1886–93

Genovese E, Angeretti MG, Ronga M, Leonardi A, Novario R, Callegari L et al. Follow-up of collagen meniscus implants by MRI. Radiol Med (Turin) 2007;112(7):1036–48

De Coninck T, Huysse W, Willemot L, Verdonk R, Verstraete K, Verdonk P. Two-year follow-up study on clinical and radiological outcomes of polyurethane meniscal scaffolds. Am J Sports Med 2013;41(1):64–72

Lynch TC, Crues JV, Morgan FW, Sheehan WE, Harter LP, Ryu R. Bone abnormalities of the knee: prevalence and significance at MR imaging. Radiology 1989;171(3):761–6

Martín-Hernández C, Ranera-García M, Díaz-Martínez JV, Muniesa-Herrero MP, Floría-Arnal LJ, Osca-Guadalajara M et al. Results of polyurethane implant for persistent knee pain after partial meniscectomy with a minimum of two years follow-up. Rev Esp Cir Ortopédica Traumatol Engl Ed 2015;59(1):44–51

Verdonk P, Beaufils P, Bellemans J, Djian P, Heinrichs EL, Huysse W et al. Successful Treatment of Painful Irreparable Partial Meniscal Defects With a Polyurethane Scaffold: Two-Year Safety and Clinical Outcomes. Am J Sports Med 2012;40(4):844–53

Butt U, Vuletić F, Stenhouse G, Hudetz D, Bradbury N. Meniscal scaffold for the treatment of partial meniscal defect-clinical and radiological outcomes in a two-year follow-up. Int Orthop. 2021;45(4):977-983

Lee W, Gan J, Lie D. Save the meniscus – Clinical outcomes of meniscectomy versus meniscal repair. J Orthop Surg 2019;27:230949901984981

Haspl M, Trsek D, Lovric D, Strahonja B, Matokovic D. Functional and magnetic resonance imaging outcome after polyurethane meniscal scaffold implantation following partial meniscectomy. Int Orthop. 2021;45(4):971-975

Li W, Pan J, Li J, Guo J, Zeng C, Xie D. Clinical application of polyurethane meniscal scaffold: A meta-analysis. J Orthop 2021;24:173-181

Leroy A, Beaufils P, Faivre B, Steltzlen C, Boisrenoult P, Pujol N. Actifit® polyurethane meniscal scaffold: MRI and functional outcomes after a minimum follow-up of 5 years. Orthop Traumatol Surg Res OTSR 2014;103(4):609–14

Monllau JC, Poggioli F, Erquicia J, Ramírez E, Pelfort X, Gelber P. Magnetic Resonance Imaging and Functional Outcomes After a Polyurethane Meniscal Scaffold Implantation: Minimum 5-Year Follow-up. Arthroscopy - Journal of Arthroscopic and Related Surgery 2018;34:1621–1627

Toanen C, Dhollander A, Bulgheroni P, Filardo G, Zaffagnini S, Spalding T et al. Polyurethane Meniscal Scaffold for the Treatment of Partial Meniscal Deficiency: 5-Year Follow-up Outcomes: A European Multicentric Study. Am J Sports Med 2020;48(6):1347-1355

Figueroa D, Figueroa F, Calvo R, Gomez C, Vaisman A. Meniscal polyurethane scaffold plus cartilage repair in post meniscectomy syndrome patients without malalignment improves clinical outcomes at mid-term follow-up. J Clin Orthop Trauma. 2020;15:16-21.

Sabater-Martos M, Chimeno-Pigrau C, Tornero Dacasa E, Sastre Solsona S, Isern Kebschull J, Popescu D. Placement of a polyurethane implant is not associated with a chondroprotective effect: comparative study with cases of isolated medial meniscectomy with at least five years of follow-up. Arch Orthop Trauma Surg. 2023;143(6):3213-3218

Dhollander A, Verdonk P, Verdonk R. Treatment of Painful, Irreparable Partial Meniscal Defects with a Polyurethane Scaffold: Midterm Clinical Outcomes and Survival Analysis. American Journal of Sports Medicine 2016;44:2615–2621

Schüttler KF, Haberhauer F, Gesslein M, Heyse TJ, Figiel J, Lorbach O. Midterm follow-up after implantation of a polyurethane meniscal scaffold for segmental medial meniscus loss: maintenance of good clinical and MRI outcome. Knee Surgery, Sports Traumatology, Arthroscopy 2016;24:1478–1484

Phua SKA, Tham SYY, Ho SWL. Does laterality matter? a systematic review and meta-analysis of clinical and survival outcomes of medial versus lateral meniscal scaffolds. Knee. 2023;40:227-237

Hirschmann A, Schiapparelli FF, Schenk L, Keller L, Amsler F, Hirschmann MT. The Genovese grading scale is not reliable for MR assessment of collagen meniscus implants. Knee 2017;24(1):9-15

Filardo G, Andriolo L, Kon E, de Caro F, Marcacci M. Meniscal scaffolds: results and indications. A systematic literature review. International Orthopaedics 2015;35–46

Houck DA, Kraeutler MJ, Belk JW, McCarty EC, Bravman JT. Similar clinical outcomes following collagen or polyurethane meniscal scaffold implantation: a systematic review. Knee Surg Sports Traumatol Arthrosc 2018;26(8):2259–69

Kohli S, Schwenck J, Barlow I. Failure rates and clinical outcomes of synthetic meniscal implants following partial meniscectomy: a systematic review. Knee Surg Relat Res. 2022;34(1):27

Zaffagnini S, Marcheggiani Muccioli GM, Lopomo N, Bruni D, Giordano G, Ravazzolo G et al. Prospective long-term outcomes of the medial collagen meniscus implant versus partial medial meniscectomy: a minimum 10-year follow-up study. Am J Sports Med 2011;39(5):977–85

Downloads

Published

24-04-2024

Issue

Section

ORTHOPAEDICS AND SURGERY

How to Cite

1.
Maione A, Ricci M, Perfetti S, Poggioli F, Calanna F, Puce M, et al. Meniscal scaffold implantation in post meniscectomy syndrome results in clinical and radiological outcomes comparable to primary subtotal meniscectomy in patients without post meniscectomy syndrome. Acta Biomed [Internet]. 2024 Apr. 24 [cited 2024 Jul. 18];95(2):e2024032. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/15425