Phenotypic expression of Hashimoto’s thyroiditis is absolutely atypical in girls with Turner syndrome

Phenotypic expression of Hashimoto’s thyroiditis is absolutely atypical in girls with Turner syndrome

Authors

  • Giuseppina Salzano Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Mariarosa Calafiore Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Cristina Mignosa Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Stefano Passanisi Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Jessica Trombatore Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy
  • Giuseppina Zirilli Department of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy

Keywords:

autoimmune thyroid disorders, chromosomopathies, epidemiological peculiarities, thyroid function presenting pattern, thyroid function evolution pattern

Abstract

Background: It is unknown whether phenotypic expression of Hashimoto’s thyroiditis (HT) might be conditioned by the association with Turner syndrome (TS). Objectives: To focus on the most recent pediatric studies concerning epidemiology and biochemical course of HT in TS girls. Design: The epidemiological peculiarities of TS-related HT in pediatric age were compared with those usually observed in non-TS girls with HT and results are summarized in Tables 1 and 2. Conclusions: 1) phenotypical expression of HT in TS girls is significantly different from that observed in girls without TS; 2) such differences concern the epidemiological picture, the biochemical presentation modes and also the natural history from HT diagnosis onwards; 3) these peculiarities of TS-related HT are not necessarily linked with a specific karyotype. 

 

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Published

13-09-2016

How to Cite

1.
Phenotypic expression of Hashimoto’s thyroiditis is absolutely atypical in girls with Turner syndrome. Acta Biomed [Internet]. 2016 Sep. 13 [cited 2024 Apr. 15];87(2):136-40. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/5325