The benefit and risk of testosterone replacement therapy in older men: effects on lipid metabolism

The benefit and risk of testosterone replacement therapy in older men: effects on lipid metabolism

Authors

  • Stefano Volpato Department of Clinical and Experimental Medicine, Section of Internal Medicine Gerontology and Geriatrics, University of Ferrara, Italy
  • Giovanni B. Vigna Department of Clinical and Experimental Medicine, Section of Internal Medicine Gerontology and Geriatrics, University of Ferrara, Italy
  • Renato Fellin Department of Clinical and Experimental Medicine, Section of Internal Medicine Gerontology and Geriatrics, University of Ferrara, Italy

Keywords:

testosterone, men, aging, lipids

Abstract

Over the last decades, testosterone replacement therapy for middle-aged and older men has been gaining increasing and widespread attention and popularity. Although several benefits of testosterone replacement therapy are well established, including but not limited to improvement in libido, body composition, and bone density, concerns for multiple potential adverse effects remain. In particular, concerns are frequently raised regarding the possibility that testosterone replacement therapy may increase the risks of prostate cancer and cardiovascular disease as consequence of a potential detrimental effect of testosterone on cardiovascular risk factors. This mini-review will present and discuss the current knowledge on the relationship between testosterone replacement therapy and change in lipid fractions in older men.

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Published

01-03-2010

Issue

Vol. 81 No. 1Suppl (2010): Proceedings of the meeting on Geriatric Endocrinology Parma,Italy,March 27-28th 2009

Section

REVIEWS

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

1.
The benefit and risk of testosterone replacement therapy in older men: effects on lipid metabolism. Acta Biomed [Internet]. 2010 Mar. 1 [cited 2024 Apr. 28];81(1Suppl):95-9. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/4642