Time for integration: communication in the immune system

Time for integration: communication in the immune system

Authors

  • Marco Vitale Department of Human Anatomy, Pharmacology & Forensic Medicine, Human Anatomy Section, University of Parma, Ospedale Maggiore, Parma, Italy

Keywords:

immunological synapse, intracellular signalling, signal integration, cytokine secretion

Abstract

Signals exchanged between cells in the immune system are generated at specific contact regions termed “immunological synapses” (IS). The morphology and the functions of IS vary with circumstances and include directing secretion and integrating positive and negative signals to tune the extent of response – a model that is essentially derived from neurosciences. Indeed, the mechanisms of signal integration and antigen decoding are not yet completely understood and many hypotheses are worked out.

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Published

01-03-2007

Issue

Vol. 78 No. 1Suppl (2007): New frontiers and modelling in neural, endocrine and immune communication

Section

ORIGINAL ARTICLES

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

1.
Vitale M. Time for integration: communication in the immune system. Acta Biomed [Internet]. 2007 Mar. 1 [cited 2024 Jul. 27];78(1Suppl):227-30. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/4623