Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis

Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis

Authors

  • Christian Compagnone II Unit of Anesthesia, Intensive Care and Pain Therapy. University Hospital of Parma, Parma, Italy
  • Fernanda Tagliaferri II Unit of Anesthesia, Intensive Care and Pain Therapy. University Hospital of Parma, Parma, Italy
  • Francesco Amato
  • Giovanna Ballerini
  • Filippo Berlinghieri
  • Laura Bertini
  • Giorgio Bordin
  • Pietro Buonavolontà
  • Alga Cascioli
  • Francesca Ceccaroni
  • Angela Cautillo
  • Alma Ciaschi
  • Lucia Maria Dodaro
  • Guido Fanelli
  • Francesca Greco
  • Paola Lesignoli
  • Ornella Martini
  • Alfonso Papa
  • Domenico Quatrone
  • William Raffaeli
  • Mediati Rocco
  • Renato Velluci

Keywords:

Scrambler therapy, chronic pain, post herpetic neuralgia, low back pain, polyneuropathy, peripheral neuropathy, persistent pain

Abstract

Background and aim: Scrambler Therapy is a novel neuromodulation that works by electrocutaneous stimulation in a non-invasive manner through C fibers surface receptors. It substitutes pain information with synthetic “non pain” information. The primary aim of this study was to analyze the efficacy and safety of Scrambler Therapy after ten sessions related to different usage conditions and different learning curves that occur in a multi-center study. Methods: 201 patients have been treated with Scrambler Therapy. All the patients were suffering from chronic pain with a mean pain NRS of 7.41 (SD 2.06) before treatment. Main causes of chronic pain: post herpetic neuralgia 18.40 %, chronic low back pain (LBP) 37.31%, polyneuropathy 10.94%, and peripheral neuropathy 14.42 %. The remaining 18.93 % included chronic pain due to other causes. Results: The difference between pre-treatment NRS 7.41 (SD 2.06) and post-treatment 1.60 (SD 2.22) was statistically significant (P< 0.0001). The mean number of sessions per patient was 10, but 39 had complete absence of pain sooner and used fewer sessions. Only 7 patients stopped treatment due to lack of results, and 2 for personal reasons not ascribable to the treatment. Stimulation pain score of 0 during treatment, and not just pain reduction, predicts long term effectiveness, so this must be pursued by optimizing electrode positioning and correct fine-tuning of stimulation intensity. Conclusion: Scrambler Therapy is an efficient and safe alternative for several different types of refractory chronic neuropathic pain, with a very rare possibility of adverse events.

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Published

14-09-2015

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Section

ORIGINAL ARTICLES

How to Cite

1.
Chronic pain treatment and scrambler therapy: a multicenter retrospective analysis. Acta Biomed [Internet]. 2015 Sep. 14 [cited 2024 Mar. 29];86(2):149-56. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/4306