VAP or poisoning; which one has more effect on patients’ outcomes in toxicological ICU?

VAP or poisoning; which one has more effect on patients’ outcomes in toxicological ICU?

Authors

  • Morteza Hashemian Department of Anesthesiology, Bahonar Hospital, Kerman Medical University, Tehran, Iran
  • Sepideh Kamalbeik Toxicological Research Center, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Parmis Haji Seyed Razi Toxicological Research Center, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Behjat Barari Toxicological Research Center, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Alireza Salimi Department of anesthesiology, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Haleh Talaie Toxicological Research Center, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Arezou Mahdavinejad Toxicological Research Center, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Keywords:

Ventilator-associated pneumonia, poisoning, incidence, ICU

Abstract

Background: Ventilator-associated pneumonia (VAP) is the main cause of acquired infections in ICUs. Every year, millions of people suffer from poisoning by various substances. Our aim was to determine the association between VAP incidence and different kinds of toxicity among Toxicological ICU (TICU) patients.  Materials and Methods: Poisoned patients with diagnosis of VAP were enrolled to our retrospective study at TICU of Loghman Hakim Hospital. Data was collected through the medical records. The statistical analysis was performed with SPSS (version 16, Chicago, IL, USA). Results: Among 675 patients with MV > 48 h, 150 patients had the diagnosis of VAP.  Mean age was 36.6 years. 74.7% were males. Intentional poisoning was 70.3%. The incidence of VAP was 22%. The higher incidence of VAP was recorded in anti depressants and opioid toxicities. The majority of bacterial isolates (81.3%) were multi drug resistance. MRSA accounted for 50.7% of VAP cases. Non survivors’ hospital length of stay (mean = 18.7days) was significantly higher than survivors (12.8). The hospital length of stay in VAP patients was highest in the Acinetobacter spp (mean > 20 days). Mortality rate of VAP cases was 18.6%. Conclusion: No specific association was detected between incidence of VAP and different kinds of toxicity, while Anti Depressants and opioids had high VAP incidence, in a Quarter of this population. It is noticeable that pesticide had the lowest incidence for its short hospitalization. In our TICU, MRSA and Acinetobacter spp were the main agents leading to VAP and prolonged ICU stay, respectively. (www.actabiomedica.it)

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Published

27-04-2015

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Section

ORIGINAL ARTICLES

How to Cite

1.
VAP or poisoning; which one has more effect on patients’ outcomes in toxicological ICU?. Acta Biomed [Internet]. 2015 Apr. 27 [cited 2024 Apr. 14];86(1):63-8. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/3804

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