Osteoarthritis and degenerative joint disease: local treatment optionsupdate

Osteoarthritis and degenerative joint disease: local treatment optionsupdate

Authors

  • B. Palmieri
  • D. Lodi
  • S. Capone

Keywords:

Intra-articular injection, hyaluronic acid, glucocorticoids, joint disease, osteoarthritis

Abstract

This review describes intra-articular drugs therapy of arthritis and degenerative joint disease) with a range of old and recent molecules with specific focus on hyaluronic acid. HA is a cartilage matrix basic component secreted by chondrocytes: it prevents cartilage degradation by a complex interpherence between metalloproteinases, pain mediators and cells. Local injections of HA improve functional activity and pain management, particularly when it is combined with other selected drugs.

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Published

01-09-2010

Issue

Vol. 81 No. 2 (2010)

Section

REVIEWS

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Authors retain the copyright for their published work. No formal permission will be required to reproduce parts (tables or illustrations) of published papers, provided the source is quoted appropriately and reproduction has no commercial intent. Reproductions with commercial intent will require written permission and payment of royalties.

How to Cite

1.
Palmieri B, Lodi D, Capone S. Osteoarthritis and degenerative joint disease: local treatment optionsupdate. Acta Biomed. 2010;81(2):94-100. Accessed February 24, 2025. https://mattioli1885journals.com/index.php/actabiomedica/article/view/316