Idiopathic hypogonadotropic hypogonadism in selective humangonadotropin deficiency in adult man: a case report

Idiopathic hypogonadotropic hypogonadism in selective humangonadotropin deficiency in adult man: a case report

Authors

  • R. Volpi
  • M. C. Ugolotti
  • A. Carbucicchio
  • R. Delsignore

Keywords:

Hypogonadotropic hypogonadism, erectile dysfunction

Abstract

We report a rare case of idiopathic hypogonadotropic hypogonadism in an adult male (31-jear-old), who underwent an endocrinological examination because of erectile dysfunction and suspected infertility. Laboratory data showed isolated gonadotropin deficiency. Magnetic resonance imaging (MRI) of the hypothalamic-pituitary unit showed no tumoral expansions. The patient was tested with gonadotropin releasing hormone (Gn-RH) (100 μg as an i.v. bolus injection). No significant LH and FSH responses were observed. Idiopathic hypogonadotropic hypogonadism is usually caused by hypothalamic lesions, however, since Gn-RH was unable to stimulate LH and FSH secretions, we supposed that our patient was affected by defective gonadotropin secretion at pituitary level.

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Published

01-12-2008

Issue

Section

CASE REPORTS

How to Cite

1.
Volpi R, Ugolotti MC, Carbucicchio A, Delsignore R. Idiopathic hypogonadotropic hypogonadism in selective humangonadotropin deficiency in adult man: a case report. Acta Biomed [Internet]. 2008 Dec. 1 [cited 2024 Jul. 26];79(3):251-4. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/1257