Multi-dimensional indices to stage idiopathic pulmonary fibrosis: a systematic review

Multi-dimensional indices to stage idiopathic pulmonary fibrosis: a systematic review

Authors

  • Camilla Rozanski Division of Respirology Western University
  • Marco Mura Division of Respirology Western University

Keywords:

Idiopathic pulmonary fibrosis. Multi-dimensional. Staging. Prognosis. Survival. Scoring system.

Abstract

Idiopathic pulmonary fibrosis (IPF) has the highest mortality rate among all interstitial lung diseases, with a mean survival time of 2 to 3 years from the time of diagnosis. Prognosis is difficult to determine, due to the recognized heterogeneous progression of the disease, as well as lack of a well recognized staging system. This in turn raises challenges when considering therapeutic options for IPF patients, such as lung transplantation, versus a more conservative approach.  Multiple independent factors have been identified as prognostic indicators in IPF, and a number of studies have proposed multi-dimensional indices that combine several parameters in order to achieve a more accurate delineation of disease progression. In this systematic review, the Pubmed database was used to identify studies in the area of multi-dimensional staging of IPF.  We analysed and critically appraised previously proposed prognostic scoring systems. Our aim is to encourage research developments in this area to help identify an optimal multi-dimensional staging system for IPF.

Author Biography

Marco Mura, Division of Respirology Western University

Assistant Professor of Medicine, Wetsern University

Staff Respirologist, London Health Science Centre

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Published

18-04-2014

Issue

Section

Review

How to Cite

1.
Rozanski C, Mura M. Multi-dimensional indices to stage idiopathic pulmonary fibrosis: a systematic review. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2014 Apr. 18 [cited 2025 Jul. 8];31(1):8-18. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/3309