Informed consent in artificial nutrition and hydration: Ethical, legal, and clinical considerations
Keywords:
artificial nutrition and hydration, bioethics, informed consent, nutritional ethic, patient autonomyAbstract
This article addresses the complex issue of informed consent in the context of Artificial Nutrition and Hydration (ANH). It explores how physicians should act when patients are unable to provide valid consent and whether explicit, legally prescribed consent is necessary or if presumed consent can be inferred from the patient's lifestyle, values, and beliefs. The necessity of detailed patient information and the evolution of the doctor-patient relationship from a paternalistic model to one recognizing patient autonomy are discussed. The article emphasizes that ANH should be administered based on informed consent, except in exceptional urgent cases where presumed consent is applicable. Ethical and legal responsibilities of physicians in ensuring clear and comprehensible information for informed decision-making are highlighted. The article concludes that adherence to guidelines should be carefully considered and contextualized, ensuring that therapeutic choices respect the patient's dignity and autonomy. This multidisciplinary approach, involving ethicists, legal experts, and family members, is essential for decisions made in the best interest of the patient.
References
Cazzato G. Il consenso informato. Prat Med Aspetti Legali. 2007;(2):65–70.
Colombetti E. Alimentazione e idratazione artificiale come problema di giustizia. Med Morale. 2009;(6).
Karaboue K. History of the first organ transplant: Blood transfusions. Med Hist. 2023;7(3):e2023049.
Karaboue MAA, Ferrara M, Bertozzi G, et al. To vaccinate or not: literacy against hesitancy. Med Hist. 2022;6(1).
Cappabianca P, Russo GM, Atripaldi U, et al. Universal Access to Advanced Imaging and Healthcare Protection: UHC and Diagnostic Imaging. Med Sci (Basel). 2021 Sep 27;9(4):61. doi: 10.3390/medsci9040061. PMID: 34698209; PMCID: PMC8544360.
Karaboue K. Dimensions of human nutrition. Progr Nutr. 2023;25(3). doi: 10.23751/pn.v25i3.14595
Karaboue K. Dimensions of human nutrition. Progr Nutr. 2023;25(3):e2023058. doi:10.23751/pn.v25i3.14595. doi: 10.23751/pn.v25i3.14595
Bartoletti E, Lacasella GV, Karaboue K, Cavalieri L. Aesthetic medicine: towards defining its own clinical role and necessary discipline. Aesthetic Med. 2024;10(1):e2024008.
Berg JW, Appelbaum PS, Lidz CW, Parker LS. Informed consent: framing the questions. Informed Consent. Oxford University Press; 2001. doi: 10.1093/oso/9780195126778.003.0006
De Luca L, Veneziano FA, Karaboue M. Late Presenters with ST-Elevation Myocardial Infarction: A Call to Action. J Clin Med. 2022 Sep 1;11(17):5169. doi: 10.3390/jcm11175169. PMID: 36079099; PMCID: PMC9457385.
Lesi C, Fabozzi MT, Valeriani L, Zoni L. Artificial nutrition and bioethics issues: medical therapy or basic assistance? Ital J Med. 2010;1:63–69. doi: 10.1016/j.itjm.2009.09.006.
Karaboue K. Bioethical aspects of prenatal diagnosis. Med Hist. 2023;7(3): e2023050. Available from: https://www.mattioli1885journals.com/index.php/MedHistor/article/view/15228
Karaboue M, La Casella G, Karaboue K, Cipolloni L, Bosco MA, De Simone S. Il dibattito in Bioetica - Health and disease: a multicultural dichotomy. Medicina E Morale. 2023;72(2):207-12. doi:10.4081/mem.2023.1236.
Karaboue M, Berritto D, Lacasella GV. Council Directive 2013/59/Euratom of 5 December 2013: medico-legal and legal-comparative study. Clin Ter. 2024;175(5):259–261. doi:10.7417/CT.2024.5127.
Cioffi A, Cecannecchia C, Baldari B, Karaboue MAA. Informal caregivers in Italy: the 'phantom zone' of welfare. Acta Biomed. 2023 Feb 13;94(1):e2023018. doi: 10.23750/abm.v94i1.13660. PMID: 36786259; PMCID: PMC9987501.
Esposito C, Hollands C, Lima M, Settimi A, Valla JS. Il consenso informato. Videochir Pediatr. Springer Milan; 2010:69–73.
Karaboue M, Massaro M, Karaboue K. When nutrition becomes artificial: a bioethical issue. Progr Nutr. 2023;25:e2023033. doi: 10.23751/pn.v25i2.14605
Lacasella GV, Karaboue K. Nutrition and hydration of patients in a persistent vegetative state. Progr Nutr. 2022;24(2):e2022136. doi:10.23751/pn.v24i4.13895. doi: 10.23751/pn.v24i4.13895
Karaboue K. Optimizing oral health care for patients in permanent vegetative state: A multidisciplinary approach. Progr Nutr. 2024;26(1):e2024011. doi: 10.23751/pn.v26i1.15800
Miniero R. Etica e consenso informato. Nutr Parenter Pediatr. Springer Milan; 2009:127–128.
Karaboue MAA, Massaro M, Lacasella G. Artificial nutrition and hydration: bioethical and biolegal profiles. Progr Nutr. 2023;25:e2023034. doi:10.23751/pn.v25i2.14592.
Rucinski JC. Famiglia, etica, consenso informato e questioni medico-legali. Chir Add Urgenza. Springer Milan; 71–75.
Karaboue MAA, Milone V, Lacasella GV, et al. What will our children do when we are gone? Med Hist. 2022;6(1):e2022013. Available from: https://www.mattioli1885journals.com/index.php/MedHistor/article/view/13141.
Sessa F, Esposito M, Cocimano G, et al. Artificial intelligence and forensic genetics: current applications and future perspectives. Appl Sci (Basel). 2024;14(5):2113. doi:10.3390/app14052113. doi: 10.3390/app14052113
Morena D, Delogu G, Volonnino G, Alessandrini S, Karaboue MAA, Arcangeli M. COVID-19 Risk Management: a Survey among Italian physicians. Clin Ter. 2023 Mar-Apr;174(2):167-179. doi: 10.7417/CT.2023.2515. PMID: 36920135.
Lacasella GV, Karaboue M. Moral Strangers, Markets and Secular Bioethics according to H. T. Engelhardt. Clin Ter. 2024 Nov-Dec;175(6):388-390. doi: 10.7417/CT.2024.5144. PMID: 39584757.
Cantisani V, Iannetti G, Miele V, et al. Addendum to the sonographic medical act. J Ultrasound. 2021 Sep;24(3):229-230. doi: 10.1007/s40477-021-00603-w. Epub 2021 Jul 9. PMID: 34241829; PMCID: PMC8363678.
Pelotti S. Con e per il consenso informato alle cure. Salute Soc. 2012;3:123–136.
Fiorini F, Granata A, Battaglia Y, Karaboue MAA. [Talking about medicine through mass media]. G Ital Nefrol. 2019 Feb;36(1):2019-vol1. Italian. PMID: 30758148.
Pironi L. Development of home artificial nutrition in Italy over a seven-year period: 2005–2012. BMC Nutr. 2017;1. doi:10.1186/s40795-017-0150-9.
Karaboue K, Berritto D, Lacasella GV. Biological existence from medicalisation to biomedicalization. Clin Ter. 2024 Sep-Oct;175(5):262-264. doi: 10.7417/CT.2024.5128. PMID: 39400088.
Karaboue MAA, Lacasella GV, Cecannecchia C, et al. End-of-life in Italy: Critical and bioethical aspects of the bill on physician-assisted suicide. Med Hist. 2022;6:e2022026. Available from: https://mattioli1885journals.com/index.php/MedHistor/article/view/13483
Lacasella GV, Karaboue K. A short history of human nutrition from prehistory to ancient civilisations. Progr Nutr. 2022;24(2):e2022135. doi:10.23751/pn.v24i4.13896.
Cervical spine injury: clinical and medico-legal overview. Radiol Med. 2023 Jan;128(1):103-112. doi: 10.1007/s11547-022-01578-2. Epub 2023 Jan 31. PMID: 36719553; PMCID: PMC9931800.
Torchia J. Artificial hydration and nutrition for the PVS patient. Natl Cathol Bioeth Q. 2003;4:719–730.
Giaconi C, Manetti AC, Turco S, et al. Post-mortem computer tomography in ten cases of death while diving: a retrospective evaluation. Radiol Med. 2022 Mar;127(3):318-329. doi: 10.1007/s11547-022-01448-x. Epub 2022 Jan 20. PMID: 35050453.
Karaboue K. Nutrition: Central practice in patient care. Progr Nutr. 2023;25(3):e2023054. doi:10.23751/pn.v25i3.14596.
Szaniszlo V, Inocent M. Some considerations about ethical dilemmas of artificial nutrition and hydration of patients in a persistent vegetative state. Ann Bioeth Clin Appl. 2020;1.
Cappabianca P, Russo GM, Atripaldi U, et al. Universal Access to Advanced Imaging and Healthcare Protection: UHC and Diagnostic Imaging. Med Sci (Basel). 2021 Sep 27;9(4):61. doi: 10.3390/medsci9040061. PMID: 34698209; PMCID: PMC8544360.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Giorgia Viola Lacasella

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Transfer of Copyright and Permission to Reproduce Parts of Published Papers.
Authors retain the copyright for their published work. No formal permission will be required to reproduce parts (tables or illustrations) of published papers, provided the source is quoted appropriately and reproduction has no commercial intent. Reproductions with commercial intent will require written permission and payment of royalties.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.