Research productivity in the genetics of papillary thyroid carcinoma (1991-2020): a bibliometric analysis

Research productivity in the genetics of papillary thyroid carcinoma (1991-2020): a bibliometric analysis

Authors

  • Mohammad Al Hamad
  • Savita Lasrado a:1:{s:5:"en_US";s:47:"Father Muller Medical College, Mangalore, India";}
  • Hassan S. Albarbari
  • Abu Waris
  • Nadeem Siddique
  • Muhammad Ajmal Khan
  • Nouf Alharbi
  • Shamim Shaikh Mohiuddin
  • Rupesh Parmar
  • Nehal A. Zeidan
  • Aqilah T. Al-Qassab
  • Ritesh G. Menezes

Keywords:

papillary thyroid carcinoma, genetics,, oncology, bibliometrics, scientometrics

Abstract

Background and aim: Papillary thyroid carcinoma accounts for 85% of thyroid follicular epithelial-derived cancers. The identification of pathogenetic mechanisms improved the understating of papillary thyroid carcinoma pathogenesis. The current study aims to examine the research productivity and trends in the genetics of papillary thyroid carcinoma from 1991 to 2020.

Methods: The Web of Science Core Collection database was searched to retrieve the relevant literature. A search string was applied and 1,741 relevant records were selected for the analysis. Bibliometric techniques were used in the statistical analysis with the help of Biblioshiny (RStudio).

Results: The growth in the number of publications was observed to be over a hundred publications per year since 2015. ‘Thyroid’ published the highest number of publications, followed by ‘Journal of Clinical Endocrinology & Metabolism’. ‘Nikiforov YE’ was identified as the most productive researcher with a total of 49 publications. Out of the top 20 most contributing researchers, seven belonged to Italy, and four were from the USA. ‘University of Pittsburgh’ contributed the highest number of publications. The top contributing countries in this field were the USA, China, and Italy. BRAF and RAS were among the frequently used keywords.

Conclusions: This bibliometric review demonstrates that investigating the genetics underlying papillary thyroid carcinoma is a rapidly growing area of research. During the last two decades, China has been a significant contributor to the field. Besides, institutions in USA and Italy have significantly contributed to research in the genetics of papillary thyroid carcinoma. (www.actabiomedica.it)

References

Thyroid Cancer — Cancer Stat Facts (nd) Retrieved August 22, 2021, from https://seercancergov/statfacts/html/thyrohtml.

Pelizzo MR, Boschin IM, Toniato A, et al. Papillary thyroid carcinoma: 35-year outcome and prognostic factors in 1858 patients. Clin Nucl Med 2007; 32: 440-4.

Fagin JA. How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapy. J Endocrinol 2004; 183: 249-56.

Kondo T, Ezzat S, Asa SL. Pathogenetic mechanisms in thyroid follicular-cell neoplasia. Nat Rev Cancer 2006; 6: 292-306.

Musa HH, Musa IH, El-Shareif M, Musa TH. Global scientific research progress in thyroid cancer: a bibliometric analysis. J Tumour 2021; 9: 579-86.

Huang F, Wang L, Jia H. Research trends for papillary thyroid carcinoma from 2010 to 2019: a systematic review and bibliometrics analysis. Medicine (Baltimore) 2021; 100: e26100.

Birkle C, Pendlebury DA, Schnell J, Adams J. Web of Science as a data source for research on scientific and scholarly activity. Quant Sci Stud 2020; 1: 363-76.

Khan AS, Ur Rehman S, AlMaimouni YK, Ahmad S, Khan M, Ashiq M. Bibliometric analysis of literature published on antibacterial dental adhesive from 1996-2020. Polymers (Basel) 2020; 12: 2848.

Tahira M, Alias RA, Bakri A. Scientometric assessment of engineering in Malaysians universities. Scientometrics 2013; 96: 865-879.

Agrawal N, Akbani R, Aksoy BA, et al. Integrated genomic characterization of papillary thyroid carcinoma. Cell.2014; 159: 676-90.

Xing M, Westra WH, Tufano RP, et al. BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer. J Clin Endocrinol Metab 2005; 90: 6373-9.

Nikiforov YE. RET/PTC rearrangement in thyroid tumors. Endocr Pathol 2002; 13: 3-16.

Nikiforov YE, Erickson LA, Nikiforova MN, Caudill CM, Lloyd RV. Solid variant of papillary thyroid carcinoma: incidence, clinical-pathologic characteristics, molecular analysis, and biologic behavior. Am J Surg Pathol 2001; 25: 1478-84.

Rabes HM, Demidchik EP, Sidorow JD, et al. Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications. Clin Cancer Res 2000; 6: 1093–103.

Xing M. BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications. Endocr Rev 2007; 28: 742-62.

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Published

01-07-2022

How to Cite

1.
Research productivity in the genetics of papillary thyroid carcinoma (1991-2020): a bibliometric analysis. Acta Biomed [Internet]. 2022 Jul. 1 [cited 2024 Mar. 29];93(3):e2022086. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/12576

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How to Cite

1.
Research productivity in the genetics of papillary thyroid carcinoma (1991-2020): a bibliometric analysis. Acta Biomed [Internet]. 2022 Jul. 1 [cited 2024 Mar. 29];93(3):e2022086. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/12576