Jawbone fibrous dysplasia: retrospective evaluation in a cases series surgically treated and short review of the literature: Jawbone fibrous dysplasia: retrospective data analysis

Gino Amleto Pacino; Salvatore Cocuzza; Giovanni Tonoli; Paolo Boscolo Rizzo; Giancarlo Tirelli; Margherita Tofanelli; Giorgio Ciprandi; Ignazio La Mantia; Antonino Maniaci; Maria Cristina Da Mosto; Giacomo Spinato

doi:10.23750/abm.v92i1.9904

Jawbone fibrous dysplasia: retrospective evaluation in a cases series surgically treated and short review of the literature

Jawbone fibrous dysplasia: retrospective data analysis

Authors

Gino Amleto Pacino Oral and Maxillo-Facial Department, Provincial Rovigo Hospital, Italy
Salvatore Cocuzza Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", ENT Section; University of Catania- Italy
Giovanni Tonoli Otorhinolaryngology Department, Provincial Rovigo Hospital (Italy)
Paolo Boscolo Rizzo Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy
Giancarlo Tirelli Department of Otorhinolaryngology-Head and Neck Surgery, Cattinara Hospital, University of Trieste, Trieste, Italy
Margherita Tofanelli Department of Otorhinolaryngology-Head and Neck Surgery, Cattinara Hospital, University of Trieste, Trieste, Italy
Giorgio Ciprandi Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy
Ignazio La Mantia Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", ENT Section; University of Catania- Italy
Antonino Maniaci Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", ENT Section; University of Catania- Italy
Maria Cristina Da Mosto Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy
Giacomo Spinato Department of Neurosciences, Section of Otolaryngology and Regional Centre for Head and Neck Cancer, University of Padova, Treviso, Italy; Department of Surgery, Oncology and Gastroenterology, Section of Oncology and Immunology, University of Padova, Padova, Italy

DOI: https://doi.org/10.23750/abm.v92i1.9904

Keywords:

Fibrous dysplasia - jawbone - bone remodelling – craniofacial dysmorphisms

Abstract

Background and aim of the work. Fibrous dysplasia is a fibro-osseous osteopathy in which the normal bone architecture is replaced by fibrous tissue and non-functional trabeculae-like osseous structures. In head and neck area monostotic or polyostotic lesions cause a progressively expanding destructive bone swelling producing cosmetic deformities and functional impairments. The aim of this article is to present a retrospective review of a clinical case series with pathologically confirmed jawbone fibrous dysplasia for over an 8-year-period.

Material and Methods. Clinical presentation and radiographic features of fibrous dysplasia affecting the jawbone skeletal area, surgical procedures performed including the reconstructive methods employed and clinical outcomes were analysed for each patient.

Results. Seven cases were classified as having monostotic fibrous dysplasia while the others four cases were classified as having polyostotic form. The mandible was most commonly involved. The most common presenting features included marked facial deformity, intraoral bulging, malocclusion and dental alterations. Aesthetic and/or functional impairments were the major indications for surgical treatment in all the patients of this series. Six patients underwent bone remodelling while in the remaining cases subtotal or total resection was performed. Bone reconstruction by means of autologous free bone grafts or revascularized free bone flaps was made in three cases.

Conclusion. The choice of the tailored therapeutic approach should be evaluated according the patient’s age, rate of growth, anatomic location, type of involvement and the presence or not of functional disturbances and cosmetic alterations. Surgery remains the best therapeutic option.

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