Genetic syndromes with localized subcutaneous fat tissue accumulation
Authors
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Vincenza Precone
MAGI Euregio, Bolzano, Italy
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Shila Barati
MAGI Euregio, Bolzano, Italy
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Stefano Paolacci
MAGI'S LAB
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Marzia Salgarello
Centre for Surgical Treatment of Lymphedema, Plastic Surgery Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Giuseppe Visconti
Centre for Surgical Treatment of Lymphedema, Plastic Surgery Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Stefano Gentileschi
Centre for Surgical Treatment of Lymphedema, Plastic Surgery Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Giulia Guerri
MAGI’s Lab, Rovereto (TN), Italy
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Lucilla Gagliardi
UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
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Barbara Aquilanti
UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
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Giuseppina Matera
UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
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Valeria Velluti
UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
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Giacinto Abele Donato Miggiano
UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Centro di Ricerche in Nutrizione Umana, Università Cattolica Sacro Cuore, Rome, Italy
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Karen L. Herbst
Department of Medicine, University of Arizona, Tucson, Arizona
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Matteo Bertelli
MAGI Euregio, Bolzano, Italy
Keywords:
Lipedema, Dercum disease, lipomatosis
Abstract
Syndromes with localized accumulation of subcutaneous fatty tissue belong to a group of genetically and phenotypically heterogeneous disorders. These diseases may show some common signs, such as nodular fat, symmetrical fat masses, obesity, fatigue, lymphedema and symmetrical lipomas (painful or otherwise). Other symptoms may be specific for the different clinical entities, enabling correct differential diagnosis. Disorders belonging to this spectrum are lipedema, generalized diffuse or nodular forms of Dercum disease, localized nodular Dercum disease and multiple symmetric lipomatosis. Here we summarize the genes involved in syndromes with localized accumulation of subcutaneous fat and the test we use for genetic analysis.
License
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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How to Cite
1.
Precone V, Barati S, Paolacci S, et al. Genetic syndromes with localized subcutaneous fat tissue accumulation.
Acta Biomed. 2019;90(10-S):90-92. doi:
10.23750/abm.v90i10-S.8767
