Application of diffusion tensor imaging (DTI) and MR-tractography in the evaluation of peripheral nerve tumours: state of the art and review of the literature

Application of diffusion tensor imaging (DTI) and MR-tractography in the evaluation of peripheral nerve tumours: state of the art and review of the literature

Authors

  • Federico Bruno Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  • Francesco Arrigoni Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  • Silvia Mariani Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  • Lucia Patriarca Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  • Pierpaolo Palumbo Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  • Raffaele Natella Department of Precision Medicine, University of Campania “L. Vanvitelli”, Napoli
  • Liheng Ma Department of Radiology, GuangDong Pharmaceutical University, Guangzhou, Cina
  • Giuseppe Guglielmi Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Foggia, Italy
  • Renato J Galzio Neurosurgery, “San Salvatore” Hospital, L’Aquila
  • Alessandra Splendiani Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  • Ernesto Di Cesare Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  • Carlo Masciocchi Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
  • Antonio Barile Department of Biotechnology and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy

Keywords:

peripheral nerve tumours, schwannoma, neurofibroma, diffusion imaging, DTI, tractography

Abstract

Peripheral nerves can be affected by a variety of benign and malignant tumour and tumour-like lesions. Besides clinical evaluation and electrophysiologic studies, MRI is the imaging modality of choice for the assessment of these soft tissue tumours. Conventional MR sequences, however, can fail to assess the histologic features of the lesions. Moreover, the precise topographical relationship between the peripheral nerve and the tumor must be delineated preoperatively for complete tumour resection minimizing nerve damage. Using Diffusion tensor imaging (DTI) and tractography, it is possible to obtain functional information on tumour and nerve structures, allowing the assess anatomy, function and biological features. In this article, we review the technical aspects and clinical application of DTI for the evaluation of peripheral nerve tumours.

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Published

24-04-2019

How to Cite

1.
Bruno F, Arrigoni F, Mariani S, Patriarca L, Palumbo P, Natella R, et al. Application of diffusion tensor imaging (DTI) and MR-tractography in the evaluation of peripheral nerve tumours: state of the art and review of the literature. Acta Biomed [Internet]. 2019 Apr. 24 [cited 2024 Jul. 20];90(5-S):68-76. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/8326