Internal nasal dilator in patients with obstructive sleep apnea

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Matteo Gelardi
Pierluigi Intiglietta
Giuseppe Porro
Vitaliano Nicola Quaranta
Onofrio Resta
Nicola Quaranta
Giorgio Ciprandi


nasal valve, internal nasal dilator, Nas-air ®, obstructive sleep apnea, respiratory parameters


The nasal valve area has the minimal cross-sectional area of the upper airways. Obstructive sleep apnea (OSA) is a common disorder. It has been reported that nasal obstruction may be associated with OSA. The aim of this study was to investigate whether the use an internal nasal dilator may be able to affect respiratory pattern in a group of patients with OSA. The use of internal nasal dilator was able to significantly reduce two relevant respiratory outcomes, such as the apnea-hypopnea index and the oxygen desaturation index, notably there was also a positive trend for the reduction of total sleep time with HbO2 <90%). Nas-air® was also able to significantly improve restorative sleep performance. In conclusion, the present study demonstrates that Nas-air® is a new internal nasal dilator potentially capable to significantly improve respiratory outcomes and sleep quality.


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