Fluorescence guided surgery in liver tumors: applications and advantages

Fluorescence guided surgery in liver tumors: applications and advantages

Authors

  • Giorgio Rossi Acute Care and Trauma Surgery Department, Maggiore Hospital of Parma, University of Parma, Italy
  • Antonio Tarasconi Acute Care and Trauma Surgery Department, Maggiore Hospital of Parma, University of Parma, Italy
  • Gianluca Baiocchi Surgical Clinic, Department of Experimental and Clinical Sciences, University of Brescia, Italy
  • Gian Luigi de' Angelis Gastroenterology and Digestive Endoscopy Unit, University Hospital of Parma, University of Parma, Parma, Italy
  • Federica Gaiani Gastroenterology and Digestive Endoscopy Unit, University Hospital of Parma, University of Parma, Parma, Italy
  • Francesco Di Mario Gastroenterology and Digestive Endoscopy Unit, University Hospital of Parma, University of Parma, Parma, Italy
  • Fausto Catena Acute Care and Trauma Surgery Department, Maggiore Hospital of Parma, University of Parma, Italy
  • Raffaele Dalla Valle Hepato-Pancreato-Biliary Surgery Department, Maggiore Hospital of Parma, University of Parma, Italy

Keywords:

liver, fluorescence, indocyanine-green, surgery, tumors

Abstract

The use of fluorescence-guided surgery for benign and malignant hepatobiliary (HPB) neoplasms has significantly increased and improved imaging methods creating new interesting perspectives. A major challenge in HPB surgery is performing radical resection with maximal preservation of the liver parenchyma and obtaining a low rate of complications. Despite the developments, visual inspection, palpation, and intraoperative ultrasound remain the most utilized tools during surgery today.  In laparoscopic and robotic HPB surgery palpation is not possible. Fluorescence imaging enables identification of subcapsular liver tumors through accumulation of indocyanine green (ICG), after preoperative intravenous injection, in cancerous tissues of hepatocellular carcinoma and in noncancerous hepatic parenchyma, around intrahepatic cholangiocarcinoma and liver metastases, and it can also be used for visualizing extrahepatic bile duct anatomy and hepatic segmental borders, increasing the accuracy and the easiness of open and minimally invasive hepatectomy.

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Published

17-12-2018

How to Cite

1.
Fluorescence guided surgery in liver tumors: applications and advantages. Acta Biomed [Internet]. 2018 Dec. 17 [cited 2024 May 18];89(9-S):135-40. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/7974

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