Evaluation of fatigue in patients with pancreatic cancer receiving chemotherapy treatment: a cross-sectional observational study

Evaluation of fatigue in patients with pancreatic cancer receiving chemotherapy treatment: a cross-sectional observational study

Authors

  • Mariacristina Di Marco Department of Specialist, Diagnostic and Experimental Medicine, Sant’Orsola - Malpighi Hospital, University of Bologna, Bologna, Italy
  • Ivan Rubbi School of Nursing, University of Bologna, Bologna, Italy
  • Agnese Baldi School of Nursing, University of Bologna, Bologna, Italy
  • Rosaria Di Lorenzo Department of Mental Health, Local Health Authority (AUSL) of Modena, Modena, Italy
  • Daniela Magnani School of Nursing, Department of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Modena, Italy
  • Valeria Cremonini School of Nursing, ASL Romagna and University of Bologna, Bologna, Italy School of Nursing, Department of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Modena, Italy
  • Leopoldo Sarli Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Giovanna Artioli Local Health Centre - Santa Maria Nuova Hospital Scientific Institute for Research, Hospitalization and Health Care, Reggio Emilia, Italy
  • Paola Ferri University of Modena and Reggio Emilia

Keywords:

Pancreatic Neoplasms, Pancreatic cancer, Fatigue, Chemotherapy, Brief Fatigue Inventory

Abstract

Background and aim of the work: Cancer-related fatigue (CRF) is one of the most common symptoms experienced by cancer patients (CPs) and negatively affects quality of life. Although CRF is frequently experienced, it is often underreported, underdiagnosed and undertreated. The objectives of this study were to evaluate the level of fatigue in patients with pancreatic cancer undergoing chemotherapy and to analyse its correlation with patients’ demographic and clinical variables. Methods: A cross-sectional observational study was implemented in the Oncology Day Hospital of a Northern Italian hospital. A sample of 48 patients receiving chemotherapy were evaluated through the Brief Fatigue Inventory Italian version (BFI-I) between 1 May and 12 October 2016. Data were statistically analysed. Results: Most of our patients (94%) experienced fatigue. Women as well as patients with an age ≥65 years reported more fatigue. Anemia, pain and a weight loss of over 16 kg in the last 6 months were significantly related to the perception of fatigue. Regarding life habits, smoking was related to high global score of BFI-I. Conclusions: In accordance with literature, our study suggests that fatigue is a frequent symptom influenced by many constitutional, clinical and environmental factors. Our results highlight the need for an early and regular evaluation of fatigue among cancer patients, in order to implement all those pharmacological and non-pharmacological interventions with proven efficacy in attenuating this symptom.

 

Author Biography

Paola Ferri, University of Modena and Reggio Emilia

Department of Diagnostic, Clinical and Public Health Medicine

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Published

27-02-2018

How to Cite

1.
Evaluation of fatigue in patients with pancreatic cancer receiving chemotherapy treatment: a cross-sectional observational study. Acta Biomed [Internet]. 2018 Feb. 27 [cited 2024 May 28];89(4-S):18-27. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/7063

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