FNA Cytology in pediatric small cell glioblastoma

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Alexandrai Kalogerak
Dimitrios Tamiolakis
Iris Zoi
Iliana Karvela-Kalogeraki
Mihailos Karvelas-Kalogerakis
John Segredakis
Galateia Datseri


Glioblastoma, Cytology, Histology


Small cell glioblastoma is a high anaplastic variant of GBM characterized by a monomorphic proliferation of small or medium cells with oval nuclei and scanty cytoplasm. Case study: The cytologic findings of a small cell glioblastoma in 11-year-old male and histologic features of the tumor using immunocytohistochemistry are reported. Conclusion: The accurate preoperative diagnosis of a small cell glioblastoma is crucial to developing a curative surgical plan. Cytology- confirmed by histology- provides a convenient, safe and effective approach to solving a challenging differential diagnosis. 



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