Multifocal meningiomatosis: A case study highlighting diagnostic and monitoring challenges

Multifocal meningiomatosis: A case study highlighting diagnostic and monitoring challenges

Authors

  • Domenico Mannatrizio Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Foggia, Italy https://orcid.org/0000-0003-3365-7132
  • Valentina Testini Radiology Unit, Barletta University Hospital, Italy https://orcid.org/0000-0003-1231-5213
  • Giacomo Fascia Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Foggia, Italy https://orcid.org/0000-0001-5244-5093
  • Francesco Saverio Guerra Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Foggia, Italy https://orcid.org/0000-0003-3923-3429
  • Federica Masino Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Foggia, Italy https://orcid.org/0009-0004-4289-3289
  • Roberto Bellitti Radiology Unit, Barletta University Hospital, Italy
  • Giuseppe Guglielmi Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Foggia, Italy; Radiology Unit, Barletta University Hospital, Italy; Department of Radiology, Hospital IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy

Keywords:

meningioma, neuro-oncology, tumor, neuroradiology, MRI, CT

Abstract

This case presentation discusses the diagnostic and monitoring challenges of a rare case of multifocal meningiomatosis in a 27-year-old female who initially presented with dizziness and migraine in 2019. Emergency CT revealed multiple formations with calcifications of extra-axial origin. Subsequent contrast-enhanced MRI exposed approximately 20 meningiomas in both cerebral and medullary locations. A comparison of MRI findings from 2019 to 2023 demonstrated an average growth of meningiomas from 3 to 5 mm. This case report emphasizes the crucial role of contrast-enhanced MRI in the diagnosis and monitoring of meningiomatosis, underscores the complexity of managing meningiomatosis and shows the importance of close clinical and radiological follow-up in determining the appropriate timing for intervention.

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Published

26-02-2025

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Section

CASE REPORTS

How to Cite

1.
Mannatrizio D, Testini V, Fascia G, et al. Multifocal meningiomatosis: A case study highlighting diagnostic and monitoring challenges. Acta Biomed. 2025;96(1):15714. doi:10.23750/abm.v96i1.15714