Functional continence in anorectal malformation after posterior sagittal anorectoplasty
Keywords:
anorectal malformation, outcome, functional, posterior sagittal anorectoplastyAbstract
Background and aim: Incontinence remains a surgical challenge for patients with anorectal malformations. This study aimed to determine the outcome function of continence in anorectal malformation patients after posterior sagittal anorectoplasty (PSARP) at Dr. Wahidin Sudirohusodo Hospital, considering gender; type of anorectal malformation; sacral ratio; vertebral, anal, cardiac, tracheal, esophageal, renal, and limb (VACTERL) anomalies; and age when undergoing PSARP.
Methods: This descriptive, analytical, cross-sectional study used primary data (Rintala questionnaire) and secondary data (medical records) at single-center hospitals in Makassar, Indonesia. It investigated 39 patients who had received PSARP over 5 years.
Results: Of the 39 patients, 24 (61.5%) were male, and 15 (38.5%) were female. The age at which PSARP was performed was £6 months for 22 (56.4%) patients and after 6 months for 17 (43.6%) patients. A relationship existed between the age when PSARP was performed and continence outcomes (p=0.034). Patients who were treated at younger than 6 months had better continence function than those who underwent PSARP after 6 months. The type of anorectal malformation has no influenced the functional outcome of PSARP: most patients with no fistula type 19 (48.7%) (p=0.198). Patients without VACTERL anomalies had better functional outcomes than patients with VACTERL anomalies.
Conclusions: Functional outcomes in anorectal malformation patients were related to the age at which PSARP was performed, type of anorectal malformation, and presence of VACTERL anomalies. The sacral ratio had no relationship with functional outcomes.
References
Askarpour S, Ostadian N, Javaherizadeh H, Mousavi SM. Outcome of patients with anorectal malformations after posterior sagittal anorectoplasty: A study from Ahvaz, Iran. Annals of Pediatric Surgery. 2014;10(3):65-67. doi:10.1097/01.XPS.0000450388.28994.70
Ghorbanpoor M, Dehvan B, Rahimi S, Pirdehghan A. Fecal Incontinence after Posterior Sagittal Anorectoplasty for Anorectal Malformation: A Single-Center Study. Scientifica (Cairo). 2018;2018. doi:10.1155/2018/8297617
Smith CA, Avansino J. Anorectal Malformations. 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–.
Wood RJ, Halleran DR, Ahmad H, et al. Assessing the benefit of reoperations in patients who suffer from fecal incontinence after repair of their anorectal malformation. J Pediatr Surg. 2020;55(10):2159-2165. doi:10.1016/j.jpedsurg.2020.06.011
Cochard LR. Netter’s Atlas of Human Embryology. Updated Ed. Saunders Elsevier; 2012.
Coran AG, Caldamone A, Adzick NS, Krummel TM. Pediatric Surgery. 7th Editio. Elsevier Inc; 2012. doi: 10.1016/C2009-0-41746-X
Han Y, Xia Z, Guo S, Yu X, Li Z. Laparoscopically Assisted Anorectal Pull-Through versus Posterior Sagittal Anorectoplasty for High and Intermediate Anorectal Malformations: A Systematic Review and Meta-Analysis. PLoS One. 2017;12(1):e0170421.
Rocourt D V., Kulaylat AS, Kulaylat AN, Leung S, Cilley RE. Primary Posterior Sagittal Anorectoplasty Outcomes for Rectovestibular and Perineal Fistulas Using an Accelerated Pathway: a Single Institution Study. J Pediatr Surg. 2019;54(9):1778-1781. doi:10.1016/j.jpedsurg.2019.05.020
Bhatnagar V. Assessment of postoperative results in anorectal malformations. J Indian Assoc Pediatr Surg. 2005;10(2):80-85. doi:10.4103/0971-9261.16466
deVries PA, Peña A. Posterior sagittal anorectoplasty. J Pediatr Surg. 1982;17(5):638-643. doi:10.1016/S0022-3468(82)80126-7
Ure BM, Rintala RJ, Holschneider AM. Scoring postoperative results. In: Holschneider AM, Hutson JM, editors. Anorectal Malformations in Children. Berlin: Springer; 2006. pp. 351–60.
Brisighelli G, Macchini F, Consonni D, Di Cesare A, Morandi A, Leva E. Continence after posterior sagittal anorectoplasty for anorectal malformations: comparison of different scores. J Pediatr Surg. 2018;53(9):1727-1733. doi:10.1016/j.jpedsurg.2017.12.020
Feng W, Mu H, Chen M, et al. Significance of searching for ganglia in the terminal rectum/fistula of complex anorectal malformations: Related to defecation function. Front Pediatr. 2023;11. doi:10.3389/fped.2023.1124647
Makrufardi F, Arifin DN, Afandy D, Yulianda D, Dwihantoro A, Gunadi. Anorectal malformation patients’ outcomes after definitive surgery using Krickenbeck classification: A cross-sectional study. Heliyon. 2020;6(2):4-8. doi:10.1016/j.heliyon.2020.e03435
Sukarnjanaprai N, Ngerncham M, Laohapensang M. The Functional Outcomes in Anorectal Malformations after Posterior Sagittal Anorectoplasty. J Med Assoc Thai. 2017;100:105-113.
van den Hondel D, Wijers CHW, van Bever Y, et al. Patients with anorectal malformation and upper limb anomalies: genetic evaluation is warranted. Eur J Pediatr. 2016;175(4):489-497. doi: 10.1007/s00431-015-2655-9
Totonelli G, Catania VD, Morini F, et al. VACTERL association in anorectal malformation: effect on the outcome. Pediatr Surg Int. 2015;31(9):805-808. doi:10.1007/s00383-015-3745-5
Macedo M, Martins JL, Freitas Filho LG. Sacral ratio and fecal continence in children with anorectal malformations. BJU Int. 2004;94(6):893-894. doi:10.1111/j.1464-410X.2004.05053.x
Zadeh AMK, Nejat F, Abbasiou P. Comparison of sacral ratio in normal children and children with urinary and/or faecal complaints. Iran J Pediatr. 2008;18(1):57-61.
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