Sexual activity and the adolescent with haemophilia

Sexual activity and the adolescent with haemophilia

Authors

  • Atanas Banchev a:1:{s:5:"en_US";s:53:"University Hospital "Tzaritza Giovanna - ISUL", Sofia";}

Keywords:

haemophilia, adolescents, sexual activity, promotion, iliopsoas bleed

Abstract

Haemophilia A and B are congenital bleeding disorders, associated with joint and soft tissue bleeding episodes. Adolescence is an important period of the individual development, associated with tendency to risky behavior in those, who suffer chronic conditions. The current review focuses on sexual health in the adolescents with haemophilia and related to sexual activity complications in the course of the disease such as iliopsoas hemorrhage and joint bleedings, models and strategies for sexual health promotion and education in this specific age group and disorder. (www.actabiomedica.it)

References

Mannucci PM. Hemophilia therapy: the future has begun. Haematologica. 2020 Mar;105(3):545-553. doi: 10.3324/haematol.2019.232132. Epub 2020 Feb 14. PMID: 32060150; PMCID: PMC7049365.

Banchev A, Stoyanova D, Avramova B, Mladenov B, Moutafchieva P, Konstantinov D. Successful intraosseous factor VIII application in a haemophilic emergency. J Clin Pharm Ther. 2021 Feb;46(1):212-214. doi: 10.1111/jcpt.13252. Epub 2020 Aug 29. PMID: 32860636.

Berntorp E, Fischer K, Hart DP, Mancuso ME, Stephensen D, Shapiro AD, Blanchette V. Haemophilia. Nat Rev Dis Primers. 2021 Jun 24;7(1):45. doi: 10.1038/s41572-021-00278-x. PMID: 34168126.

Banchev A, Batorova A, Faganel Kotnik B, Kiss C, Puras G, Zapotocka E, Zupancic-Salek S; Patient Advocacy Group. A Cross-National Survey of People Living with Hemophilia: Impact on Daily Living and Patient Education in Central Europe. Patient Prefer Adherence. 2021 Apr 28;15:871-883. doi: 10.2147/PPA.S303822. PMID: 33953547; PMCID: PMC8091596.

Schramm W. The history of haemophilia - a short review. Thromb Res. 2014 Nov;134 Suppl 1:S4-9. doi: 10.1016/j.thromres.2013.10.020. Epub 2014 Feb 7. PMID: 24513149.

Hassan S, Monahan RC, Mauser-Bunschoten EP, van Vulpen LFD, Eikenboom J, Beckers EAM, Hooimeijer L, Ypma PF, Nieuwenhuizen L, Coppens M, Schols SEM, Leebeek FWG, Smit C, Driessens MH, le Cessie S, van Balen EC, Rosendaal FR, van der Bom JG, Gouw SC. Mortality, life expectancy, and causes of death of persons with hemophilia in the Netherlands 2001-2018. J Thromb Haemost. 2021 Mar;19(3):645-653. doi: 10.1111/jth.15182. Epub 2020 Dec 18. PMID: 33217158; PMCID: PMC7986360.

Wyrwich KW, Krishnan S, Poon JL, Auguste P, von Maltzahn R, Yu R, von Mackensen S. Interpreting important health-related quality of life change using the Haem-A-QoL. Haemophilia. 2015 Sep;21(5):578-84. doi: 10.1111/hae.12642. Epub 2015 Mar 31. PMID: 25828456.

Barger, D. (2022). Sexual Function and Quality of Life: Assessing Existing Tools and Considerations for New Technologies. In: Wac, K., Wulfovich, S. (eds) Quantifying Quality of Life. Health Informatics. Springer, Cham. https://doi.org/10.1007/978-3-030-94212-0_16.

World Health Organization. Defining sexual health: report of a technical consultation on sexual health, 28-31 January 2002, Geneva. World Health Organization, 2006.

Dorner TE, Stronegger WJ, Rebhandl E, Rieder A, Freidl W. The relationship between various psychosocial factors and physical symptoms reported during primary-care health examinations. Wien Klin Wochenschr. 2010 Feb;122(3-4):103-9. doi: 10.1007/s00508-010-1312-6. PMID: 20213377.

Parish KL. Sexuality and haemophilia: connections across the life-span. Haemophilia. 2002 May;8(3):353-9. doi: 10.1046/j.1365-2516.2002.00647.x. PMID: 12010433.

Blamey G, Buranahirun C, Buzzi A, Cooper DL, Cutter S, Geraghty S, Saad H, Yang R. Hemophilia and sexual health: results from the HERO and B-HERO-S studies. Patient Relat Outcome Meas. 2019 Aug 14;10:243-255. doi: 10.2147/PROM.S211339. PMID: 31616195; PMCID: PMC6698588.

https://www.who.int/health-topics/adolescent-health#tab=tab_1.

Louis-Jacques J, Samples C. Caring for teens with chronic illness: risky business? Curr Opin Pediatr. 2011 Aug;23(4):367-72. doi: 10.1097/MOP.0b013e3283481101. PMID: 21602681.

Rew L. Sexual health promotion in adolescents with chronic health conditions. Fam Community Health. 2006 Jan-Mar;29(1 Suppl):61S-9S. doi: 10.1097/00003727-200601001-00010. PMID: 16344638.

Everett Jones S, Lollar DJ. Relationship between physical disabilities or long-term health problems and health risk behaviors or conditions among US high school students. J Sch Health. 2008 May;78(5):252-7; quiz 298-9. doi: 10.1111/j.1746-1561.2008.00297.x. PMID: 18387024.

Joan-Carles Suris, Núria Parera, Sex, drugs and chronic illness: health behaviours among chronically ill youth, European Journal of Public Health, Volume 15, Issue 5, October 2005, Pages 484–488, https://doi.org/10.1093/eurpub/cki001.

Nylander C, Seidel C, Tindberg Y. The triply troubled teenager--chronic conditions associated with fewer protective factors and clustered risk behaviours. Acta Paediatr. 2014 Feb;103(2):194-200. doi: 10.1111/apa.12461. Epub 2013 Dec 3. PMID: 24117768.

Ibrahim N, Hassler C, Jousselme C, Barry C, Lefèvre H, Falissard B, Bouyer J, Rouquette A. Chronic conditions, subjective wellbeing and risky sexual behaviour among adolescents and young adults. Eur J Pediatr. 2023 Jan 5. doi: 10.1007/s00431-022-04784-2. Epub ahead of print. PMID: 36602622.

Canaro M, Goranova-Marinova V, Berntorp E. The ageing patient with haemophilia. Eur J Haematol. 2015 Feb;94 Suppl 77:17-22. doi: 10.1111/ejh.12497. PMID: 25560790.

Blamey G, Van Tassel B, Sagermann E, Stain AM, Waterhouse L, Iorio A. Sexual issues in people with haemophilia: Awareness and strategies for overcoming communication barriers. Haemophilia. 2022 Jan;28(1):36-41. doi: 10.1111/hae.14447. Epub 2021 Nov 16. PMID: 34784071; PMCID: PMC9299037.

Dune T. Sexual expression, fulfilment and haemophilia: reflections from the 16th Australian and New Zealand Haemophilia Conference. Haemophilia. 2012 May;18(3):e138-9. doi: 10.1111/j.1365-2516.2011.02743.x. Epub 2012 Jan 5. PMID: 22221992.

Tobase P, Mahajan A, Francis D, Leavitt AD, Giermasz A. A gap in comprehensive care: Sexual health in men with haemophilia. Haemophilia. 2017 Jul;23(4):e389-e391. doi: 10.1111/hae.13276. Epub 2017 Jun 2. PMID: 28574623.

Fromme A, Dreeskamp K, Pollmann H, Thorwesten L, Mooren FC, Völker K. Participation in sports and physical activity of haemophilia patients. Haemophilia. 2007 May;13(3):323-7. doi: 10.1111/j.1365-2516.2007.01456.x. PMID: 17498083.

Sherlock E, O'Donnell JS, White B, Blake C. Physical activity levels and participation in sport in Irish people with haemophilia. Haemophilia. 2010 Jan;16(1):e202-9. doi: 10.1111/j.1365-2516.2009.02111.x. Epub 2009 Oct 29. PMID: 19878332.

Goto M, Haga N, Takedani H. Physical activity and its related factors in Japanese people with haemophilia. Haemophilia. 2019 Jul;25(4):e267-e273. doi: 10.1111/hae.13773. Epub 2019 May 27. PMID: 31132810.

Tiktinsky R, Kenet G, Dvir Z, Falk B, Heim M, Martinowitz U, Katz-Leurer M. Physical activity participation and bleeding characteristics in young patients with severe haemophilia. Haemophilia. 2009 May;15(3):695-700. doi: 10.1111/j.1365-2516.2009.01990.x. Epub 2008 Feb 27. PMID: 19298376.

Kennedy, M., O’Gorman, P., Monaghan, A., Lavin, M., O’Mahony, B., O’Connell, N.M., O’ Donnell, J.S., Turecek, P.L., Gormley, J. and (2021), A systematic review of physical activity in people with haemophilia and its relationship with bleeding phenotype and treatment regimen. Haemophilia, 27: 544-562. https://doi.org/10.1111/hae.14282.

Heijnen L. The role of rehabilitation and sports in haemophilia patients with inhibitors. Haemophilia. 2008 Nov;14 Suppl 6:45-51. doi: 10.1111/j.1365-2516.2008.01889.x. PMID: 19134033.

Thorson AI. Sexual activity and the cardiac patient. Am J Geriatr Cardiol. 2003 Jan-Feb;12(1):38-40. doi: 10.1111/j.1076-7460.2003.01755.x. PMID: 12502914.

Chen X, Zhang Q, Tan X. Cardiovascular effects of sexual activity. Indian J Med Res. 2009 Dec;130(6):681-8. PMID: 20090128.

Frappier J, Toupin I, Levy JJ, Aubertin-Leheudre M, Karelis AD. Energy expenditure during sexual activity in young healthy couples. PLoS One. 2013 Oct 24;8(10):e79342. doi: 10.1371/journal.pone.0079342. PMID: 24205382; PMCID: PMC3812004.

Rodriguez-Merchan EC, Goddard NJ. Muscular bleeding, soft-tissue hematomas and pseudotumors. In: Rodriguez-Merchan EC, Goddard NJ, Lee CA, eds. Musculoskeletal Aspects of Hemophilia. Oxford: Blackwell Science, 2000: 85–91.

Pearson AG, Macnaughton LS, Hind K. Sex differences in the impact of resistance exercise load on muscle damage: A protocol for a randomised parallel group trial. PLoS One. 2022 Sep 29;17(9):e0275221. doi: 10.1371/journal.pone.0275221. PMID: 36174033; PMCID: PMC9521925.).

Blamey G, In: Sexual health in haemophilia. Canada: 6-7). This is especially the case of the iliopsoas muscle.

Gianotten WL, Heijnen L. Haemophilia, aging and sexuality. Haemophilia. 2009 Jan;15(1):55-62. doi: 10.1111/j.1365-2516.2008.01914.x. PMID: 19149847.

E. Carlos Rodriguez-Merchan & Hortensia De la Corte-Rodriguez (2020) Iliopsoas hematomas in people with hemophilia: diagnosis and treatment, Expert Review of Hematology, 13:8, 803-809, DOI: 10.1080/17474086.2020.1787146.

Balkan C, Kavakli K, Karapinar D. Iliopsoas haemorrhage in patients with haemophilia: results from one centre. Haemophilia. 2005 Sep;11(5):463-7. doi: 10.1111/j.1365-2516.2005.01123.x. PMID: 16128889.

Peters M, Henny CP, ten Cate JW, Marsman JW, Breederveld C. Lumbar arterial rupture secondary to iliopsoas hemorrhage in a hemophiliac patient. Acta Haematol. 1984;71(2):128-9. doi: 10.1159/000206571. PMID: 6421052.

Serban M, Mihailov D, Savescu D, Bordos D, Talpos Niculescu S, Jinca C, Lăcătuşu A, Siebeck M, Schramm W. Long-term outcome of an unusual haemophilic pseudotumour. Hamostaseologie. 2012;32 Suppl 1:S43-4. PMID: 22960649.

Kulkarni R, Soucie JM. Pediatric hemophilia: a review. Semin Thromb Hemost. 2011 Oct;37(7):737-44. doi: 10.1055/s-0031-1297164. Epub 2011 Dec 20. PMID: 22187396.

Gualtierotti R, Solimeno LP, Peyvandi F. Hemophilic arthropathy: Current knowledge and future perspectives. J Thromb Haemost. 2021 Sep;19(9):2112-2121. doi: 10.1111/jth.15444. Epub 2021 Jul 27. PMID: 34197690; PMCID: PMC8456897.

Mauser-Bunschoten E. In: Sexuality and Bleedig disorders. Utrecht – Van Creveldkliniek, 2014

Batorova A, Boban A, Brinza M, Lissitchkov T, Nemes L, Zupan Preložnik I, Smejkal P, Zozulya N, Windyga J. Expert opinion on current and future prophylaxis therapies aimed at improving protection for people with hemophilia A. J Med Life. 2022 Apr;15(4):570-578. doi: 10.25122/jml-2022-0103. PMID: 35646171; PMCID: PMC9126455.

Moretti L, Bizzoca D, Buono C, Ladogana T, Albano F, Moretti B. Sports and Children with Hemophilia: Current Trends. Children (Basel). 2021 Nov 19;8(11):1064. doi: 10.3390/children8111064. PMID: 34828778; PMCID: PMC8625282.

Helland Y, Garratt A, Kjeken I, Kvien TK, Dagfinrud H. Current practice and barriers to the management of sexual issues in rheumatology: results of a survey of health professionals. Scand J Rheumatol. 2013;42(1):20-6. doi: 10.3109/03009742.2012.709274. Epub 2012 Sep 21. PMID: 22994142.

Dyer K, das Nair R. Why don't healthcare professionals talk about sex? A systematic review of recent qualitative studies conducted in the United kingdom. J Sex Med. 2013 Nov;10(11):2658-70. doi: 10.1111/j.1743-6109.2012.02856.x. Epub 2012 Jul 30. PMID: 22846467.

Downloads

Published

24-04-2023

Issue

Section

PEDIATRICS AND ADOLESCENT MEDICINE

How to Cite

1.
Banchev A. Sexual activity and the adolescent with haemophilia. Acta Biomed. 2023;94(2):e2023003. doi:10.23750/abm.v94i2.14168