A rare case of Ovarian Juvenile Granulosa Cell Tumor in an Infant with Isosexual Pseudo Puberty and a Revision of Literature : A 9-month-old female with ovarian granulosa cell tumor

Vincenzo De Sanctis; Shayma  Ahmed; Ashraf Soliman; Fawzia Alyafei; Nada  Alaaraj; Maryam Al Maadheed; Colin Clelland

doi:10.23750/abm.v92i4.11572

A rare case of Ovarian Juvenile Granulosa Cell Tumor in an Infant with Isosexual Pseudo Puberty and a Revision of Literature

A 9-month-old female with ovarian granulosa cell tumor

Authors

Vincenzo De Sanctis Quisisana Hospital, Ferrara
Shayma Ahmed Pediatric Endocrinology Department, Hamad Medical Corporation
Ashraf Soliman Pediatric Endocrinology Department, Hamad Medical Corporation
Fawzia Alyafei Pediatric Endocrinology Department, Hamad Medical Corporation
Nada Alaaraj Pediatric Endocrinology Department, Hamad Medical Corporation
Maryam Al Maadheed Pediatrics Endocrinology Department, Sidra Medicine- Doha
Colin Clelland Pediatrics Pathology Department, Sidra Medicine, Doha

DOI: https://doi.org/10.23750/abm.v92i4.11572

Keywords:

Precocious puberty, infant, ovary, granulosa cell tumor, estrogen.

Abstract

Juvenile ovarian granulosa cell tumors (JGCTs) are described infrequently in pediatrics, and their finding in infants is exceptional. We highlight the presenting symptoms, radiologic images, operative management, and histopathologic findings of a 9-month-old female with isosexual pseudopuberty. An updated revision of literature in infants below the age of 12 months is also reported.

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