Distrectual osteosarcopenia in limb disuse: case report and mini literature review

Distrectual osteosarcopenia in limb disuse: case report and mini literature review

Authors

  • Gabriele Filoni 2nd Orthopedic and Traumatologic Clinic, University of Pisa, Pisa, Italy https://orcid.org/0000-0002-5060-4908
  • Michele Di Lonardo 2nd Orthopedic and Traumatologic Clinic, University of Pisa, Pisa, Italy
  • Giovanni Mandile 2nd Orthopedic and Traumatologic Clinic, University of Pisa, Pisa, Italy
  • Lorenzo Andreani 2nd Orthopedic and Traumatologic Clinic, University of Pisa, Pisa, Italy
  • Francesca Falossi Orthopedic Rehabilitation Department Section, University of Pisa, Pisa, Italy
  • Alessandro Franchi Division of Surgical, Molecular and Ultrastructural Pathology, University of Pisa, Pisa, Italy
  • Vanna Bottai 2nd Orthopedic and Traumatologic Clinic, University of Pisa, Pisa, Italy
  • Rodolfo Capanna 2nd Orthopedic and Traumatologic Clinic, University of Pisa, Pisa, Italy

Keywords:

Osteoporosis, osteosarcopenia, disuse, BMU

Abstract

Osteosarcopenia is a new concept of association of osteoporosis and sarcopenia. Both of these pathologies are more frequent in old people and general affects all the skeleton with increased risk of falls and fractures, loss of global function, fragility, and mortality, but also surgical failures.

The coexistence of these condition derives from a close relationship, not only anatomical, between bone and muscle tissues. Sometimes these pathological conditions can involve only a skeleton segment, due to local disuse, causing a district form of sarcopenia. In this clinical case, Authors describes a case of isolated lower limb osteosarcopenia in a young non-osteoporotic patient, due to a prolonged limb disuse, complicated by surgical treatment failure for previous pathology, diagnosed by clinical, laboratory, instrumental and histopathological exams.

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Published

30-12-2020

How to Cite

1.
Filoni G, Di Lonardo M, Mandile G, Andreani L, Falossi F, Franchi A, et al. Distrectual osteosarcopenia in limb disuse: case report and mini literature review. Acta Biomed [Internet]. 2020 Dec. 30 [cited 2024 Jul. 18];91(14-S):e2020005. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/10785