The regarding the call to explore the unexpected low severity of COVID-19 in Sub-Saharan Africa

Main Article Content

Luis Fonte
Maria Ginori
Gissel García


Saharan Africa, SARS CoV-2, COVID 19, Severity, attenuating factors




Download data is not yet available.
Abstract 3 |


Yang J, Zheng Y, Gou X, Pu K, Chen Z, et al. Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis. Int J Infect Dis 2020: 94: 91-95. doi.
World Health Organization. Coronavirus press conference, 11 February 2020. Geneva: WHO, 2020. Available in: 2020-final.pdf?sfvrsn=e2019136_2
World Health Organization. Coronavirus disease 2019 (COVID-19): Weekly Epidemiological Update, 25 September 2020. Geneva: WHO, 2020.
Napoli P, Nioi M. Global spread of Coronavirus Disease 2019 and Malaria: An epidemiological paradox in the early stage of a pandemic. J Clin Med 2020: 9: 1138. doi: 10.3390/jcm9041138
Diop BZ, Ngom M, Pougué Biyong C, Pougué Boyong JN. The relatively young and rural population may limit the spread and severity of COVID-19 in Africa: a modelling study. BMJ Glob Health 2020; 5: e002699. doi: 10.1136/bmjgh-2020-002699.
World Health Organization. World malaria report, 2018.
Krishan K, Kanchan T. Novel Coronavirus (SARS-CoV-2) resistance in African populations: A cause worth exploring. Acta Biomed 2020; 91: e2020023 DOI: 10.23750/abm.v91i3.9872
Cortegiani A, Ingoglia G, Ippolito M, Giarratano A, Einav S. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19. J Crit Care 2020; 59:176–190.
Eastman R, Fidock D. Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria. Nat Rev Microbiol 2009; 7: 764-774.
Hays R, Pierce D, Giacomin P, Loukas A, Bourke P, McDermott R. Helminth coinfection and COVID-19: An alternate hypothesis. PLoS Negl Trop Dis 2020; 14: e0008628.
Fonte L, Acosta A, Sarmiento ME, Ginori M, García G, Norazmi MN. COVID 19 lethality in Sub-Saharan Africa and helminth immune modulation. Front Immunol 2020; 11: doi: 10.3389/fimmu.2020.574910