To prevent the allergic disease: the dream of the allergist

Main Article Content

Giorgio Ciprandi
Amelia Licari
Gian Luigi Marseglia

Keywords

allergy, children, prevention, treatments

Abstract

Allergen avoidance, allergen immunotherapy, IgE antagonists, biological medications, prevention and treatment of respiratory infections, probiotics, adapted formula, vitamins, and oligo-elements have been investigated as strategies in the prevention of allergic diseases. Promising findings were obtained. To prevent allergic diseases could be a dream that will be soon realized in clinical practice.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...
Abstract 16 | PDF Downloads 7

References

1) Stróżek J, Samoliński BK, Kłak A, Gawińska-Drużba E, Izdebski R, Krzych-Fałta E, et al. The indirect costs of allergic diseases. Int J Occup Med Environ Health. 2019;32:281-290
2) Pawankar, R.; Canonica, G.; Holgate, S.; Lockey, R.; Blaiss, M. (Eds.) World Allergy Organisation (WAO) White Book on Allergy: Update 2013; World Allergy Organization: Milwaukee, WI, USA, 2013
3) Caffarelli C, Santamaria F, Mastrorilli C, Santoro A, Iovane B, Petraroli M, Gaeta V, et al. Report on advances for pediatricians in 2018: allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroenterology, infectious diseases, neonatology, nutrition, respiratory tract disorders and surgery. Ital J Pediatr. 2019;45:126
4) Van den Elsen LWJ, Garssen J, Burcelin R, Verhasselt V. Shaping the gut microbiota by breastfeeding: the gateway to allergy prevention? Frontiers in Pediatrics 2019;7:47
5) Wang HT, Anvari S, Anagnostou K. The role of probiotics in preventing allergic disease. Children 2019;6,24
6) Yepes-Nuñez JJ, Brożek JL, Fiocchi A, Pawankar R, Cuello-García C, Zhang Y, et al. Vitamin D supplementation in primary allergy prevention: Systematic review of randomized and non-randomized studies. Allergy. 2018;73:37-49
7) Saggese G, Vierucci F, Prodam F, Cardinale F, Cetin I, Chiappini E, et al. Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of preventive and social pediatrics, jointly with the Italian federation of pediatricians. It J Ped 2018;44:51
8) Falzon CC, Balabanova A. Phytotherapy: An Introduction to Herbal Medicine. Prim Care. 2017;44:217-227
9) Colalto C. What phytotherapy needs: Evidence-based guidelines for better clinical practice. Phytother Res. 2018;32:413-425
10) Ipci K, Oktemer T, Muluk NB, Şahin E, Altıntoprak N, Bafaqeeh SA, et al. Alternative products to treat allergic rhinitis and alternative routes for allergy immunotherapy. Am J Rhinol Allergy. 2016;30:8-10
11) Ciprandi G, Pronzato C, Ricca V, Varese P, Del Giacco GS. Terfenadine exerts antiallergic activity reducing ICAM-1 expression on nasal epithelial cells in patients with pollen allergy. Clin Exp Allergy 1995;25:871-878
12) Ciprandi G, Ricca V, Truffelli T, Bertolini C, Fiorino N, Riccio AM, et al.. Seasonal rhinitis and azelastine: long or short term treatment? J Allergy Clin Immunol 1997;99:301-7
13) Ciprandi G, Signori A, Tosca MA, Cirillo I. Spirometric abnormalities in patients with allergic rhinitis: indicator of an asthma march? Amer J Rhinol Allergy 2011;32:22-8
14) Ciprandi G, Cirillo I, Klersy C, Marseglia GL, Vizzaccaro A, Pallestrini E, Tosca MA Role of FEF25-75 as an early marker of bronchial impairment in patients with seasonal allergic rhinitis. Am J Rhinol 2006;20:641-7
15) Cirillo I, Marseglia GL, Klersy C, Ciprandi G Allergic patients have more numerous and prolonged respiratory infections than non-allergic subjects. Allergy 2007;62(9):1087-90
16) Yao Y, Wang ZC, Wang N, Zhou PC, Chen CL, Song J, et al. Allergen immunotherapy improves defective follicular regulatory T cells in patients with allergic rhinitis. J Allergy Clin Immunol. 2019;144:118-128
17) Wallrapp A, Riesenfeld SJ, Burkett PR, Kuchroo VK. Type 2 innate lymphoid cells in the induction and resolution of tissue inflammation. Immunol Rev. 2018;286:53-73
18) Mikhail I, Grayson MH. Asthma and viral infections: An intricate relationship. Ann Allergy Asthma Immunol. 2019;123:352-358
19) Vandini S, Biagi C, Fischer M, Lanari M. Impact of Rhinovirus Infections in Children. Viruses. 2019;11:6
20) Esposito S, Soto-Martinez ME, Feleszko W, Jones MH, Shen KL, Schaad UB. Nonspecific immunomodulators for recurrent respiratory tract infections, wheezing and asthma in children: a systematic review of mechanistic and clinical evidence. Curr Opin Allergy Clin Immunol. 2018;18:198-209

Most read articles by the same author(s)