Allergen immunotherapy in children and adolescents with respiratory diseases

Allergen immunotherapy in children and adolescents with respiratory diseases

Authors

  • Maria Angela Tosca Allergy Center, Department of Pediatrics, Istituto G. Gaslini, Genoa, Italy
  • Amelia Licari Pediatrics Clinic, Department of Pediatrics, Ospedale San Matteo, University of Pavia, Pavia, Italy
  • Roberta Olcese Allergy Center, Department of Pediatrics, Istituto G. Gaslini, Genoa, Italy
  • Riccardo Castagnoli Pediatrics Clinic, Department of Pediatrics, Ospedale San Matteo, University of Pavia, Pavia, Italy https://orcid.org/0000-0003-0029-9383
  • Alessia Marseglia Pediatrics Clinic, Department of Pediatrics, Ospedale San Matteo, University of Pavia, Pavia, Italy
  • Gian Luigi Marseglia Pediatric Clinic Department of Pediatrics, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy
  • Michele Miraglia del Giudice Department of Woman, Child and of General and Specialized Surgery. University of Campania"Luigi Vanvitelli" Naples, Italy
  • Alberto Martelli Department of Pediatrics, G.Salvini Hospital, Garbagnate Milanese, Milan, Italy
  • Mauro Calvani UOC di Pediatria. Azienda Ospedaliera S. Camillo Forlanini, Roma, Italy
  • Carlo Caffarelli Clinica Pediatrica, Dipartimento di Medicina e Chirurgia, Università di Parma, Italy
  • Marzia Duse Department of Pediatrics, Sapienza University, Rome, Italy
  • Claudio Cravidi Agenzia Tutela della Salute, ATS (National Healthcare System), Pavia, Italy
  • Fabio Cardinale Department of Pediatrics and Emergency, Pediatric Allergy and Pulmunology Unit, Azienda Ospedaliera-Universitaria Consorziale-Policlinico, Ospedale Pediatrico Giovanni XXIII, Bari, Italy
  • Giorgio Ciprandi Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.

Keywords:

allergen-specific immunotherapy, subcutaneous immunotherapy, sublingual immunotherapy, allergic asthma, children

Abstract

To date, the only disease-modifying treatment strategy for allergic rhinitis and asthma is allergen immunotherapy (AIT). There is evidence that AIT improves allergic rhinitis and asthma, such as reducing symptom severity and medication use and improving of quality of life, with a long-lasting effect after the end of the course. The recent clinical trials evidenced AIT effectiveness and safety in allergic asthma. Consequently, the current version of the GINA (Global Initiative for Asthma) guidelines recommend AIT as an add-on therapy for asthma. There is also evidence that AIT may exert preventive activity on the possible progression from allergic rhinitis to asthma in children and the onset of new sensitizations.

References

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Published

15-09-2020

How to Cite

1.
Tosca MA, Licari A, Olcese R, et al. Allergen immunotherapy in children and adolescents with respiratory diseases. Acta Biomed. 2020;91(11-S):e2020006. doi:10.23750/abm.v91i11-S.10309