Idiopathic Pulmonary Fibrosis (IPF) incidence and prevalence in Italy

Idiopathic Pulmonary Fibrosis (IPF) incidence and prevalence in Italy

Authors

  • Nera Agabiti Departement of Epidemiology, Regional Health Service of Lazio, Rome
  • Maria Assunta Porretta Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy
  • Lisa Bauleo Departement of Epidemiology, Regional Health Service of Lazio, Rome
  • Angelo Coppola Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy
  • Gianluigi Sergiacomi Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy
  • Armando Fusco Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy
  • Francesco Cavalli Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy
  • Maria Cristina Zappa Pneumology Service, S. Pertini Hospital, Rome
  • Rossana Vignarola Pneumology Service, S. Pertini Hospital, Rome
  • Stefano Carlone Pneumology Service, San Giovanni Addolorata Hospital, Rome
  • Gianpiero Facchini Pneumology Service, San Giovanni Addolorata Hospital, Rome
  • Salvatore Mariotta 5Pneumology Service, Sant’Andrea Hospital, La Sapienza University, Rome
  • Paolo Palange Internal Medicine I Division, Umberto I Hospital, La Sapienza University Rome
  • Salvatore Valente Pneumology Service, A. Gemelli Hospital, Catholic University, Rome
  • Giovanna Pasciuto Pneumology Service, A. Gemelli Hospital, Catholic University, Rome
  • Gabriella Pezzuto Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy
  • Augusto Orlandi Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy
  • Danilo Fusco Departement of Epidemiology, Regional Health Service of Lazio, Rome
  • Marina Davoli Departement of Epidemiology, Regional Health Service of Lazio, Rome
  • Cesare Saltini Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy
  • Ermanno Puxeddu Departement of Biomedicine and Prevention, Tor Vergata University, and the Respiratory Medicine, Radiology and Pathology Units, Tor Vergata University Hospital, Rome, Italy

Keywords:

Idiopathic pulmonary fibrosis, epidemiology, ICD9-CM

Abstract

Background: Studies of Idiopathic Pulmonary Fibrosis (IPF) epidemiology show regional variations of incidence and prevalence; no epidemiological studies have been carried out in Italy. Objective: To determine incidence and prevalence rates of IPF in the population of a large Italian region. Methods: in this cross-sectional study study data were collected on all patients of 18 years of age and older admitted as primary or secondary idiopathic fibrosing alveolitis (ICD9-CM 516.3) to Lazio hospitals, from 1/1/2005 to 31/12/2009, using regional hospital discharge, population and cause of death databases. Reporting accuracy was assessed on a random sample of hospital charts carrying the ICD9-CM 516.3, 516.8, 516.9 and 515 codes, by reviewing radiology and pathology findings to define cases as IPF “confident”, “possible” or “inconsistent”. Results: Annual prevalence and incidence of IPF were estimated at 25.6 per 100,000 and 7.5 per 100,000 using the ICD9-CM code 516.3 without chart audit while they were estimated at 31.6 per 100,000 and at 9,3 per 100,000 for the IPF “confident” definition after hospital chart audit. Conclusion: The data provide a first estimate of IPF incidence in Italy and indicate that incidence and prevalence in southern European regions may be similar to those observed in northern Europe and North America.

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Published

20-10-2014

Issue

Vol. 31 No. 3 (2014)

Section

Original Articles: Clinical Research

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

1.
Agabiti N, Porretta MA, Bauleo L, Coppola A, Sergiacomi G, Fusco A, et al. Idiopathic Pulmonary Fibrosis (IPF) incidence and prevalence in Italy. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2014 Oct. 20 [cited 2025 Mar. 10];31(3):191-7. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/3695