Predictive Value of Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio in Patients with Hypersensitivity Pneumonia: Platelet-To-Lymphocyte Ratio And Neutrophil-To-Lymphocyte Ratio In Hypersensitivity Pneumonia

Fatma Demirci Üçsular; Gulru Polat; Gülistan Karadeniz; Aysu Ayrancı; Merve Keskin; Melih Büyükşirin; Filiz Güldaval; Enver Yalnız

doi:10.36141/svdld.v37i4.9966

Predictive Value of Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio in Patients with Hypersensitivity Pneumonia

Platelet-To-Lymphocyte Ratio And Neutrophil-To-Lymphocyte Ratio In Hypersensitivity Pneumonia

Authors

Fatma Demirci Üçsular Dr. Suat Seren Chest Diseases and Surgery Research and Training Hospital
Gulru Polat Dr. Suat Seren Chest Diseases and Surgery Research and Training Hospital
Gülistan Karadeniz Dr. Suat Seren Chest Diseases and Surgery Research and Training Hospital
Aysu Ayrancı Dr. Suat Seren Chest Diseases and Surgery Research and Training Hospital
Merve Keskin Dr. Suat Seren Chest Diseases and Surgery Research and Training Hospital
Melih Büyükşirin Dr. Suat Seren Chest Diseases and Surgery Research and Training Hospital
Filiz Güldaval Dr. Suat Seren Chest Diseases and Surgery Research and Training Hospital
Enver Yalnız Dr. Suat Seren Chest Diseases and Surgery Research and Training Hospital

Keywords:

platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, acute/chronic hypersensitivity pneumonia

Abstract

Aim: To evaluate Platelet-to-Lymphocyte Ratio (PLR) and Neutrophil-to-Lymphocyte Ratio (NLR) in patients with HP.

Method: A sample of 140 total patients, 50 having chronic HP and 20 having acute HP, and a control group of 70 more patients were included in this retrospective study conducted with hospital Ethical Committee approval.

Results: PLR and NLR values were significantly higher in all HP patients than in the control group ( p <0.001). In addition, these biomarkers were significantly higher in patients with acute HP than in the chronic HP group (p = 0.017 and p = 0.044, respectively). The cutoff values for PLR and NLR were:

177 (p = 0.020) and 2.76 (p <0.0001) between the HP patients and the control group, and,
110 (p = 0.0054) and 2.15 (p = 0.03), between the acute and chronic HP groups.

Conclusion: PLR and NLR values are inexpensive and easy parameters that can guide in diagnosing hypersensitivity pneumonia and the acute-chronic differentiation of the disease.

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Published

16-12-2020

Issue

Vol. 37 No. 4 (2020)

Section

Original Articles: Clinical Research

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

Demirci Üçsular F, Polat G, Karadeniz G, Ayrancı A, Keskin M, Büyükşirin M, et al. Predictive Value of Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio in Patients with Hypersensitivity Pneumonia: Platelet-To-Lymphocyte Ratio And Neutrophil-To-Lymphocyte Ratio In Hypersensitivity Pneumonia. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2020 Dec. 16 [cited 2025 Mar. 11];37(4):e2020012. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/9966

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