Predictive Value of Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio in Patients with Hypersensitivity Pneumonia Platelet-To-Lymphocyte Ratio And Neutrophil-To-Lymphocyte Ratio In Hypersensitivity Pneumonia

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Fatma Demirci Üçsular
Gulru Polat
Gülistan Karadeniz
Aysu Ayrancı
Merve Keskin
Melih Büyükşirin
Filiz Güldaval
Enver Yalnız

Keywords

platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, acute/chronic hypersensitivity pneumonia

Abstract

Aim: To evaluate Platelet-to-Lymphocyte Ratio (PLR)   and Neutrophil-to-Lymphocyte Ratio (NLR)  in patients with HP.


Method: A sample of 140 total patients, 50 having chronic HP and 20 having acute HP, and a  control group of 70 more patients were included in this retrospective study conducted with hospital  Ethical Committee approval.


Results: PLR and NLR values ​​were significantly higher in all HP patients than in the control group ( p <0.001). In addition, these biomarkers were significantly higher in patients with acute HP than in the chronic HP group (p = 0.017 and p = 0.044, respectively).  The cutoff values ​​for PLR and NLR were:



  • 177 (p = 0.020) and 2.76 (p <0.0001) between the HP patients and the control group, and,

  • 110 (p = 0.0054) and 2.15 (p = 0.03), between the acute and chronic HP groups.


Conclusion: PLR and NLR values ​​are inexpensive and easy parameters that can guide in diagnosing hypersensitivity pneumonia and the acute-chronic differentiation of the disease.

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