A prospective study of patients diagnosed with sarcoidosis: Factors - environmental exposure, health assessment, and genetic outlooks

A prospective study of patients diagnosed with sarcoidosis: Factors - environmental exposure, health assessment, and genetic outlooks

Authors

  • Louis B. Caruana Texas State University
  • Gerald D. Redwine Texas State University http://orcid.org/0000-0003-0167-0324
  • Rodney E. Rohde Texas State University
  • Chris J. Russian Texas State University

Keywords:

Sarcoidosis, Environmental Exposure, Genetic

Abstract

This original research is a directional study that determined the habits of individuals using four analyses to find statistical significance in the data collected from the surveys of 801 qualified of 1,340 individuals who agreed to participate. Results from the self-reported diagnosis of individuals affected by sarcoidosis produced seven statistically significant indicators of future research needed. The demographics revealed a significantly greater number of women and African-Americans participants than other minorities in the United States and suggested a sense of urgency to find a cure. Most important are the seven statistically significant findings that also gave credence to the researchers’ four subdiagnostic classifications. They are acute sarcoidosis (AS) and chronic sarcoidosis with limited dissemination (CSLD), while more severe cases include those with chronic sarcoidosis with full dissemination including cutaneous involvement (CSFDIC) and chronic sarcoidosis with neurosarcoidosis (CSN). The most severe sarcoidosis cases (CSN) were on the “most likely” side of every statistically significant category except drinking alcohol, and the “least likely” to participate in physical activities. Conversely, the least severe case of sarcoidosis (AS) was the opposite. The complete list of statistically significant areas was related to alcohol use, tobacco use, ciprofloxacin use, environmental exposure to metals (copper, iron), infectious diseases (candidiasis), genetics, and physical exercise. Statistically, the most crucial study needed; emerged from the Rh blood grouping of the participants.

Author Biographies

Louis B. Caruana, Texas State University

Clinical Laboratory Science Program, Retired Emeritus

Gerald D. Redwine, Texas State University

Clinical Laboratory Science Program, Associate Professor

Rodney E. Rohde, Texas State University

Associate Professor and Chair, Clinical Laboratory Science Program

Chris J. Russian, Texas State University

Associate Professor and Program Coordinator for the Master of Science, Department of Respiratory Care 

Published

16-09-2019

Issue

Section

Original Articles: Clinical Research

How to Cite

1.
Caruana LB, Redwine GD, Rohde RE, Russian CJ. A prospective study of patients diagnosed with sarcoidosis: Factors - environmental exposure, health assessment, and genetic outlooks. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2019 Sep. 16 [cited 2025 Mar. 11];36(3):228-42. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/7112