A case report of steroid resistant cardiac sarcoidosis successfully managed with methotrexate

A case report of steroid resistant cardiac sarcoidosis successfully managed with methotrexate

Authors

  • Olga Grabowska Mazovian Center For Treatment of Lung Diseases and Tuberculosis, Otwock, Poland
  • Magdalena M Martusewicz-Boros 3rd Lung Diseases Dept., National TB & Lung Diseases Research Institute, Warsaw, Poland
  • Dorota Piotrowska-Kownacka 1st Department of Clinical Radiology, Medical University of Warsaw, Poland
  • Elżbieta Wiatr 3rd Lung Diseases Dept., National TB & Lung Diseases Research Institute, Warsaw, Poland

Abstract

Up to one fourth of sarcoidosis patients may have cardiac involvement, what is potentially a life-threatening condition and requires aggressive treatment. Corticosteroids are generally effective in cardiac sarcoidosis, however may have significant short and long term adverse effects. We present a case of a 42-year-old male, who was diagnosed with pulmonary and cardiac sarcoidosis. He was treated initially with corticosteroids and satisfactory improvement was achieved in the lungs but not in the heart. Methotrexate was added as a second line therapy, being beneficial for the heart as well as steroid sparing agent. Cardiac improvement was documented during serial CMR imaging.

Downloads

Published

01-07-2018

Issue

Section

Case Reports

How to Cite

1.
Grabowska O, Martusewicz-Boros MM, Piotrowska-Kownacka D, Wiatr E. A case report of steroid resistant cardiac sarcoidosis successfully managed with methotrexate. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2018 Jul. 1 [cited 2025 Mar. 7];35(2):178-81. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/6554