Primary Pulmonary MALT-Lymphoma Mimicking Pulmonary Infection: a Case Report and Overview on the Pertinent Literature

Abstract

Primary pulmonary extra-nodal MALT-lymphomas are very uncommon. Clinical-radiological pattern is variable and usually non-specific and a correct diagnosis usually requires the histopathological examination. Herein we report a case of a 59-year-old man presented with dyspnea at the slightest effort and dry cough. At imaging multiple pulmonary consolidations with interlobular septal thickenings and ground-glass opacities were disclosed, defining a crazy paving pattern. The surgical approach was necessary to reach the diagnosis of primary pulmonary low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT-lymphoma). Immunotherapy (Rituximab) and chemotherapy (Bendamustine) were started leading to a progressive improvement of the disease.