New attempt in tuberculosis treatment: autologous cytokine-induced killer after chemotherapy treatment failure in a case of multi-drug resistant tuberculosis(MTB)

New attempt in tuberculosis treatment: autologous cytokine-induced killer after chemotherapy treatment failure in a case of multi-drug resistant tuberculosis(MTB)

Authors

  • Junchi Xu
  • XinNian Chen
  • ZhiJian Ye
  • Meiying Wu
  • Cuilin Shi
  • Peijun Tang
  • Hui Chen
  • Xiaoyan Zhu
  • Huafeng Song
  • Ping Xu

Keywords:

Cell therapy, multi-drug resistant tuberculosis, CIK

Abstract

A 32-year-old woman was diagnosed as pulmonary tuberculosis 15 years ago and recurred several times due to long-term nonstandard treatment. Drug sensitivity test indicated that multidrug-resistant tuberculosis had emerged and we determined relevant therapeutic schedule according to this result. However, it didn’t show any amelioration of the disease after 3-month chemotherapy. We formulated 3-course CIK immunotherapy based on patient’s condition. After 3 courses of immunotherapy, we found obvious amelioration of the patient’s condition. And there was no recurrence during the follow-up in the past 3 years. Therefore, we considered that the CIK immunotherapy is an effective method for tuberculosis treatment and recurrence prevention.

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Published

28-04-2017

Issue

Section

Case Reports

How to Cite

1.
Xu J, Chen X, Ye Z, Wu M, Shi C, Tang P, et al. New attempt in tuberculosis treatment: autologous cytokine-induced killer after chemotherapy treatment failure in a case of multi-drug resistant tuberculosis(MTB). Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2017 Apr. 28 [cited 2025 Apr. 10];34(1):97-9. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/5084