Sarcoidosis as a risk factor for venous thromboembolism.

Sarcoidosis as a risk factor for venous thromboembolism.

Authors

  • Anna Goljan Geremek National Tuberculosis and Lung Diseases Research Institute, Warsaw Poland
  • Witold Tomkowski National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland
  • Marcin Geremek Wolski Hospital, Warsaw, Poland
  • Elzbieta Puscinska National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland
  • Grzegorz Malek National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland
  • Adam Nowinski National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland
  • Michal Bednarek National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland
  • Pawel Sliwinski National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland

Keywords:

sarcoidosis, pulmonary embolism, inflammation

Abstract

Sarcoidosis as a chronic condition of immune dysregulation might be associated with increased risk of venous thromboembolism (VTE). In this study we report three cases of sarcoidosis and pulmonary embolism (PE) occurring together, that share common clinical, serological and pathological findings, confirming the diagnosis of active pulmonary sarcoidosis and no others co-existing prothrombotic factors. We hypothesized that the hypercoagulability and increased risk for VTE in sarcoidosis may be attributable to active local and generalized inflammatory process. The possible relation of clinical picture of sarcoidosis that favors thrombus formation and the bidirectional inflammation and coagulation process are discussed. Further investigation of PE in patients with sarcoidosis are required as the co-incidence of both diseases seems to be more frequent than expected.

 

Author Biographies

Anna Goljan Geremek, National Tuberculosis and Lung Diseases Research Institute, Warsaw Poland

2nd Department of Respiratory Medicine

Witold Tomkowski, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland

Cardio-pulmonary Intensive Care Unit

Marcin Geremek, Wolski Hospital, Warsaw, Poland

Department of vascular surgery

Elzbieta Puscinska, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland

2nd Department of Respiratory Medicine

Grzegorz Malek, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland

Department of Radiology and Diagnostic Imaging

Adam Nowinski, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland

2nd Department of Respiratory Medicine

Michal Bednarek, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland

2nd Department of Respiratory Medicine

Pawel Sliwinski, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland

4th Department of Respiratory Medicine

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Published

25-08-2017

Issue

Section

Case Series

How to Cite

1.
Goljan Geremek A, Tomkowski W, Geremek M, Puscinska E, Malek G, Nowinski A, et al. Sarcoidosis as a risk factor for venous thromboembolism. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2017 Aug. 25 [cited 2025 Apr. 2];34(2):170-8. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/4911