Solely lung-involved IgG4-related disease : a case report and review of the literature

Solely lung-involved IgG4-related disease : a case report and review of the literature

Authors

  • Xiao-Qin Zhang Department of Respirology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, China
  • Guo-Ping Chen Department of Endocrinology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China
  • Sheng-Chang Wu Department of Respirology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, China
  • Sa Yu Department of Respirology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, China
  • Hong Wang Department of Respirology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, China
  • Xuan-Yi Chen Department of Respirology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, China
  • Zhuo-Chao Ren Department of Respirology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, China

Keywords:

IgG4-related disease, Immunoglobulin G4, Lung

Abstract

By analyzing the clinical data of 1 case of IgG4-related lung disease(IgG4-RLD) and the review of literature, the author investigated the clinical characteristics of IgG4-RLD. IgG4-RLD is a rare disease characterized by significant elevation of serum IgG4 and infiltration of a large number of IgG4+ plasma cells. The clinical manifestations of the disease were nonspecific, and the imaging features were mixed with several types. The disease can only be involved in the lung, but also multiple organ involvement. Solely lung-involved IgG4-RD is not only extremely rare but also easily misdiagnosed as tuberculosis, lung cancer, lymphoma and other common pulmonary diseases. Histopathological examination is the key to the diagnosis of the disease. Corticosteroids are the first choice of treatment, and the overall prognosis is good.

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Published

23-12-2016

Issue

Vol. 33 No. 4 (2016)

Section

Case Reports

License

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How to Cite

1.
Zhang X-Q, Chen G-P, Wu S-C, Yu S, Wang H, Chen X-Y, et al. Solely lung-involved IgG4-related disease : a case report and review of the literature. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2016 Dec. 23 [cited 2025 Jun. 4];33(4):398-406. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/4785