Pulmonary metastases from low grade sarcoma in a patient with pulmonary sarcoidosis. Sarcoidosis or sarcoid-like reaction?

Pulmonary metastases from low grade sarcoma in a patient with pulmonary sarcoidosis. Sarcoidosis or sarcoid-like reaction?

Authors

  • Maria Majori Unità Operativa di Pneumologia e Endoscopia Toracica, Azienda Ospedaliero-Universitaria di Parma
  • Miriam Anghinolfi
  • Letizia Gnetti
  • Angelo Gianni Casalini

Keywords:

Sarcoidosis, Sarcoid-like reactions, Sarcoma

Abstract

An asymptomatic man with previous histopatological diagnosis of pulmonary sarcoidosis in radiological follow-up (stable for about 4 years) presented massive right pleural effusion. After drainage, CT of the chest showed an increase in number and size of pulmonary nodules compared to the last check (8 months before). Surgical pulmonary biopsies were performed with the diagnosis of metastases from low grade sarcoma. The primary tumor was localized to the right buttock. Given the absence of symptoms, the extent of disease and many comorbidities the patient underwent only treatment with gemcitabine that was not tolerated and discontinued after the first few cycles 1 year ago. At the present the patientis still asymptomatic even if the CT of the chest shows a slow but continuous progression of the disease. The question is: is this an association between sarcoidosis and malignancy? or was this a sarcoid-like reaction during malignancy? 

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Published

01-08-2016

Issue

Section

Case Reports

How to Cite

1.
Majori M, Anghinolfi M, Gnetti L, Casalini AG. Pulmonary metastases from low grade sarcoma in a patient with pulmonary sarcoidosis. Sarcoidosis or sarcoid-like reaction?. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2016 Aug. 1 [cited 2025 Jun. 22];33(2):171-4. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/4765