Chronic bronchiolitis in ankylosing spondylitis

Chronic bronchiolitis in ankylosing spondylitis

Authors

  • David Marquette 1 CHRU Tours, Hôpital Bretonneau, Service de Pneumologie et Explorations Fonctionnelles Respiratoires
  • Elisabeth Diot Inserm U 1100, Faculté de Médecine, Université François Rabelais, Tours, France; Service de Médecine Interne
  • Anne de Muret CHRU Tours, Service d’anatomopathologie, Tours, France
  • Olivier Favelle CHRU Tours, service de radiologie, Tours
  • Alain Sonneville CHRU Tours, Unité de surveillance continue, Tours
  • Saloua Mammou CHRU Tours, service de Rhumatologie, Tours
  • Pascal Dumont Service de Chirurgie Thoracique, CHRU Tours, Hôpital Trousseau
  • Patrice Diot CHRU Tours, Hôpital Bretonneau, Service de Pneumologie et Explorations Fonctionnelles Respiratoires; Inserm U 1100, Faculté de Médecine, Université François Rabelais, Tours, France
  • sylvain Marchand-Adam CHRU Tours, Hôpital Bretonneau, Service de Pneumologie et Explorations Fonctionnelles Respiratoires; Inserm U 1100, Faculté de Médecine, Université François Rabelais, Tours, France

Keywords:

Ankylosing spondylitis, Bronchiolitis, Dyspnea

Abstract

The pleuro-pulmonary signs of ankylosing spondylitis are generally asymptomatic, typically represented by biapical lung fibrosis. To our knowledge, the severe bronchiolitis which is sometimes observed in other spondyloarthropathies has not been described in ankylosing spondylitis. We report two cases of severe chronic bronchiolitis in ankylosing spondylitis patients. Their clinical and radiological presentation were similar, characterized by progressive deterioration of stage III-IV dyspnea, non-reversible obstructive ventilatory defect, and CT scan showing air trapping with mosaic attenuation and ground-glass opacity in expiration. Lung biopsies confirmed the diagnosis of severe follicular bronchiolitis in one patient and constrictive bronchiolitis is suspected in the other. Only the patient with follicular bronchiolitis responded positively to treatment with low doses of macrolides

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Published

25-11-2013

Issue

Vol. 30 No. 3 (2013)

Section

Case Reports

License

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How to Cite

1.
Marquette D, Diot E, de Muret A, Favelle O, Sonneville A, Mammou S, et al. Chronic bronchiolitis in ankylosing spondylitis. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2013 Nov. 25 [cited 2025 Apr. 10];30(3):231-6. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/2891