Successful pregnancy complicated by persistent pneumothorax in a patient with lymphangioleiomyomatosis (LAM) on sirolimus
Keywords:
Lymphangioleiomyomatosis, LAM, pregnancy, sirolimus, pneumothoraxAbstract
We report a successful pregnancy in a patient with longstanding LAMon treatment with sirolimus. During temporary discontinuation fo sirolimus in early pregnancy, lung function declined but recovered after resumption of sirolimus. Pregnancy was complicated by a persistent pneumothorax which was treated surgically postnatally. The child has had a normal development despite exposure to low dose sirolimus intermittently during early embryonal and mid-fetal life.Downloads
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