Coexistent sarcoidosis mimics metastasis in a patient with early-stage non-small cell lung cancer: a case report: Coexistent Sarcoidosis and NSCLC

Coexistent sarcoidosis mimics metastasis in a patient with early-stage non-small cell lung cancer: a case report

Coexistent Sarcoidosis and NSCLC

Authors

  • Xiang Zhao Peking University First Hospital
  • Yuan Cheng Peking University First Hospital
  • Wei Wang Peking University First Hospital

Keywords:

Sarcoidosis, NSCLC, Metastasis;

Abstract

Background and aim: Sarcoidosis is a granulomatous disease. Malignant tumors are accompanied rarely by granuloma reactions that mimic metastasis. Methods: We present the case of a patient with possible advanced lung cancer with metastases to the mediastinal lymph nodes and bilateral ilia. Results: Ilium biopsy revealed the presence of sarcoid-like reaction. Bronchoscopy and endobronchial ultrasound revealed an adenocarcinoma in the right upper lung lobe, with a negative mediastinal lymph node. The correct staging of lung cancer was achieved through pathological examination of the surgically removed lung tissues. Two years later, the lung cancer metastasized, and the patient underwent systemic treatment. Conclusions: Coexistent sarcoid-like reaction may mimic metastatic lung cancer. A multidisciplinary approach and sequential diagnostic biopsies can prevent unnecessary surgery or inadequate treatment by distinguishing between coexistent sarcoidosis and metastatic lung cancer.

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Published

26-03-2024

Issue

Section

Case Reports

How to Cite

1.
Zhao X, Cheng Y, Wang W. Coexistent sarcoidosis mimics metastasis in a patient with early-stage non-small cell lung cancer: a case report: Coexistent Sarcoidosis and NSCLC. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2024 Mar. 26 [cited 2025 May 20];41(1):e2024008. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/14700